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Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates
Published on: September 5, 2017
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[Tuberculosis among children and adolescents]
Victor Dahl Mathiasen1, Alexandra Kruse, Christian Wejse
1victordahl@gmail.com.
Ugeskrift for Laeger
|March 7, 2020
Summary
Diagnosing childhood tuberculosis (TB) is challenging due to vague symptoms. Early referral for suspected active or latent TB in children is crucial for disease control and elimination efforts.
Area of Science:
- Pediatrics
- Infectious Diseases
- Public Health
Background:
- Childhood tuberculosis (TB) presents diagnostic challenges due to subtle symptoms.
- Children face a higher risk of severe disease progression compared to adults.
- Pediatric TB signifies ongoing community transmission and faltering public health control.
Purpose of the Study:
- To review the clinical presentation of childhood TB.
- To outline current management strategies for pediatric TB.
- To emphasize the need for improved diagnostic and preventive measures.
Main Methods:
- This study is a review of existing literature on childhood TB.
- It synthesizes information on diagnosis, presentation, and management.
- Focuses on the implications of TB in children for disease control.
Main Results:
- TB in children is difficult to diagnose but indicates community transmission.
- Children are more vulnerable to severe TB progression.
- Current diagnostic tests may not adequately predict disease progression.
Conclusions:
- A low threshold for referral of children with suspected active or latent TB is recommended.
- Development of tests to predict progression is warranted.
- Targeting latent TB infection is essential for TB elimination.
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