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Systemic and Gastrohepatic Mucormycosis in Dogs.

R C Alves1, J S Ferreira1, A S Alves1

  • 1Hospital Veterinário, Universidade Federal de Campina Grande, Patos, Paraíba, Brazil.

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Summary

Two poodles died from mucormycosis, a fungal infection affecting multiple organs. Diagnosis involved characteristic lesions and identifying Rhizopus arrhizus, with suspected immunosuppression as a factor.

Keywords:
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Area of Science:

  • Veterinary Pathology
  • Mycology
  • Immunology

Background:

  • Mucormycosis is a severe fungal infection.
  • Systemic involvement can be rapidly fatal in dogs.
  • Gastrointestinal and hepatic manifestations are less common.

Observation:

  • Two male poodles presented with respiratory, neurological, and gastrointestinal signs.
  • Case 1 showed systemic mucormycosis affecting lungs, heart, and brain.
  • Case 2 exhibited gastric rupture and hepatic lesions with fungal hyphae.

Findings:

  • Histopathology revealed pyogranulomas, vasculitis, thrombosis, and fungal hyphae.
  • Immunohistochemistry confirmed Rhizopus arrhizus as the causative agent.
  • Rapid progression to death occurred within 3 and 19 days.

Implications:

  • This highlights the potential for severe, fatal mucormycosis in dogs.
  • Suspected underlying immunosuppression warrants further investigation.
  • Early diagnosis and treatment are critical for managing canine mucormycosis.