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"Liquid Gold" - The unTAPped Potential of Cerebrospinal Fluid Analysis?
Isabella C Glitza Oliva1, Hussein A Tawbi2,3
1Department of Melanoma Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas.
Abstract:
Obtaining blood and cerebrospinal fluid is generally less invasive than standard tumor biopsy, and are increasingly used to develop surrogate biomarkers. Leptomeningeal disease, a devastating complication of cancer, represents a unique opportunity for using liquid biopsies for diagnosis, treatment, and to elucidate underlying mechanisms of resistance to therapy.See related article by Smalley et al., p. 2163.

