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Updated: Jul 24, 2026

Guidelines for Elective Pediatric Fiberoptic Intubation

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Published on: January 17, 2011

Fatal Transdermal Fentanyl Patch Overdose in a Child.

Mark A Hilado¹, Ariana Getz¹, Rachel Rosenthal¹

¹Pediatrics, University of Southern California Keck School of Medicine, Los Angeles, USA.

|March 7, 2020

Summary

Improper disposal of fentanyl patches poses a severe risk to children. Even used patches can cause fatal overdose, as standard drug screens may not detect fentanyl.

Keywords:

fatal fentanyl overdose patch

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Fentanyl Analog Screening using LC-TIMS-TOF MS/MS

Fentanyl Analog Screening using LC-TIMS-TOF MS/MS

Published on: November 8, 2024

Area of Science:

Toxicology
Pediatric Emergency Medicine
Pharmacology

Background:

Fentanyl patches are potent opioid analgesics.
Accidental pediatric exposure to transdermal medications is a significant concern.

Observation:

A previously healthy 3-year-old girl became unresponsive after contact with a discarded fentanyl patch.
Clinical presentation included global cerebral edema, leading to brain death.

Findings:

Initial urine drug screen was negative for opiates.
Specific urine assay confirmed fentanyl and norfentanyl exposure.
Used fentanyl patches can retain sufficient active drug to cause toxicity.

Implications:

Highlights the critical need for safe storage and disposal of fentanyl patches.
Emphasizes that standard drug screens may miss synthetic opioids like fentanyl.
Necessitates physician education on advising caregivers about fentanyl patch risks and proper handling.