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Updated: Dec 27, 2025

Ex Vivo Infection of Human Lymphoid Tissue and Female Genital Mucosa with Human Immunodeficiency Virus 1 and Histoculture
Published on: October 12, 2018
GOT SHINGLES? TEST FOR HIV. Severe shingles as first presenting infection in HIV/AIDS patient
Catherine Brahe1, Rachel Ellis2
13rd Battalion 6th Marines, 2D Marine Division, PSC Box 20100, Camp Lejeune, North Carolina 28542-20100, United States.
Abstract:
Late diagnosis of HIV is associated with increased morbidity and mortality. Infected individuals need to be identified early and started on antiretroviral therapy to increase their survival and to limit transmission to the community. Historically speaking, late diagnosis has been a common occurrence in the United States, despite the majority of those patients having had a medical encounter in the year prior to their diagnosis. These visits represent missed opportunities for HIV testing and therefore delays in initiation of appropriate antiretroviral therapy. Herpes zoster is a common infection that may indicate a weakened immune system, and as such should prompt consideration for HIV testing, even in patients who lack or deny classic risk factors such as "risky sexual behavior" or drug use. Here, we present a case of severe herpes zoster in a middle aged woman with no other HIV risk factors, who was tested and found to be HIV positive. Her CD4 count at diagnosis was <200 cells/mcL, consistent with AIDS.
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