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Renal Frame Count and High Blood Pressure

H Gocer1, M Günday2, M Ünal3

  • 1İzmir Medicalpark Hospital, Cardiology, İzmir, Turkey.

La Clinica Terapeutica
|March 7, 2020
PubMed

Insights

Hypertension stage correlates with renal perfusion. Higher hypertension stages (Stage 2) show increased mean renal frame count (RFC), indicating reduced renal perfusion and potential renal function decline.

Area of Science:

  • Nephrology
  • Cardiology
  • Radiology

Background:

  • Hypertension is a major risk factor for cardiovascular and renal diseases.
  • Renal perfusion is crucial for maintaining kidney function.
  • The JNC-8 classification provides standardized hypertension staging.

Purpose of the Study:

  • To investigate the relationship between hypertension stages (JNC-8) and mean renal frame count (RFC).
  • To assess RFC as an indicator of renal perfusion in hypertensive patients.

Main Methods:

  • Retrospective analysis of 100 hypertensive patients without obstructive renal artery disease.
  • Evaluation using selective renal angiography and calculation of mean renal frame count (RFC).
  • Patients categorized into Stage 1 and Stage 2 hypertension groups based on JNC-8 criteria.

Main Results:

  • No significant differences in age, sex, hypertension duration, or lab markers between groups.
  • Stage 2 hypertensive patients exhibited significantly higher mean RFC compared to Stage 1 patients (p<0.001).
  • Mean RFC was significantly elevated in both kidneys of Stage 2 hypertensive patients.

Conclusions:

  • Mean renal frame count (RFC) increases with higher hypertension stages.
  • RFC serves as a potential indicator of renal perfusion and an indirect marker of renal function.
  • A statistically significant correlation exists between mean RFC and JNC-8 hypertension stages, suggesting slower renal artery flow with increased blood pressure.
Abstract

Keywords:
HypertensionHypertension stagesRenal angiographyRenal arteryRenal frame count

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