Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Angle Closure Glaucoma: Treatment

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...

Open Angle Glaucoma: Treatment

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

The face inversion effect and its influence on intraoperative evaluation during ptosis surgery: results of a survey of Canadian oculoplastic surgeons.

Canadian journal of ophthalmology. Journal canadien d'ophtalmologie·2026

Same author

A Case of External Beam Radiation Therapy Induced Corneal Damage in the Treatment of Squamoid Eccrine Ductal Carcinoma.

Advances in radiation oncology·2026

Same author

Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease (MOGAD): Mechanisms, Syndromes, and Management.

International ophthalmology clinics·2025

Same author

A 33-month-old boy with bilateral corneal disease.

Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus·2025

Same author

Impact of removal of the lateral orbital rim on intraorbital pressure during endoscopic trans-orbital approach (ETOA): a cadaveric study.

Acta neurochirurgica·2025

Same author

The right to sight: a call for ophthalmic care standards in carceral and detention centre settings.

Eye (London, England)·2025

Search research articles

Related Experiment Video

Updated: Dec 27, 2025

Author Spotlight: Minimally Invasive Relief for Occipital Neuralgia at the Nuchal Line

Author Spotlight: Minimally Invasive Relief for Occipital Neuralgia at the Nuchal Line

Published on: September 13, 2024

Superonasal Transconjunctival Optic Nerve Sheath Decompression: A Simplified Technique for Safe and Efficient

Andrew T Melson¹, Jacob D Warmath, Annie Moreau

¹Dean McGee Eye Institute, University of Oklahoma, Oklahoma City, Oklahoma.

Journal of Neuro-Ophthalmology : the Official Journal of the North American Neuro-Ophthalmology Society

|March 7, 2020

Summary

A modified transconjunctival optic nerve sheath decompression (ONSD) is safe and effective for treating vision loss in idiopathic intracranial hypertension (IIH). This surgical technique improved visual fields and reduced papilledema with minimal complications.

More Related Videos

Optic Nerve Transection: A Model of Adult Neuron Apoptosis in the Central Nervous System

Optic Nerve Transection: A Model of Adult Neuron Apoptosis in the Central Nervous System

Published on: May 12, 2011

Transconjunctival Approach for Injection into the Rat Optic Nerve

Transconjunctival Approach for Injection into the Rat Optic Nerve

Published on: April 4, 2025

Related Experiment Videos

Last Updated: Dec 27, 2025

Author Spotlight: Minimally Invasive Relief for Occipital Neuralgia at the Nuchal Line

Author Spotlight: Minimally Invasive Relief for Occipital Neuralgia at the Nuchal Line

Published on: September 13, 2024

Optic Nerve Transection: A Model of Adult Neuron Apoptosis in the Central Nervous System

Optic Nerve Transection: A Model of Adult Neuron Apoptosis in the Central Nervous System

Published on: May 12, 2011

Transconjunctival Approach for Injection into the Rat Optic Nerve

Transconjunctival Approach for Injection into the Rat Optic Nerve

Published on: April 4, 2025

Area of Science:

Ophthalmology
Neurosurgery

Background:

Idiopathic intracranial hypertension (IIH) can cause severe, permanent vision loss.
Optic nerve sheath decompression (ONSD) is an effective treatment for progressive vision loss in IIH patients unresponsive to medical management.

Purpose of the Study:

To introduce a modified transconjunctival technique for ONSD.
To evaluate the safety, efficacy, and efficiency of this modified ONSD in IIH patients.

Main Methods:

Retrospective case series of 66 IIH patients undergoing superonasal transconjunctival ONSD (stOND).
Data collected from January 2013 to February 2017.
Primary outcomes included visual field mean deviation, papilledema grading (Frisen scale), and visual acuity.

Main Results:

No operative complications or postoperative diplopia were reported.
Median papilledema grading decreased by 3 points (P < 0.0001).
Humphrey Visual Field mean deviation improved significantly (+1.91, P = 0.0052).

Conclusions:

The superonasal transconjunctival ONSD (stOND) is a safe, efficient, and effective surgical option for IIH-related vision loss.
This technique demonstrates reduced complication rates and significant efficacy.
Further research is needed to define optimal timing and indications for stOND in refractory IIH.