Cap-Assisted Chromo-Colonoscopy: Are 2 Techniques Better Than None?

Cap-assisted and chromo-colonoscopy are 2 techniques which may increase adenoma detection; however, chromo-colonoscopy is limited by increased time requirement. In this edition of The American Journal of Gastroenterology, Kim et al. present data from a randomized controlled trial comparing standard colonoscopy with an arm using both techniques (CAP/CHROMO). The indigo carmine was applied using a simpler method than previous studies, resulting in shorter times. The CAP/CHROMO adenoma detection was higher than the controls (54.4% vs 44.9%; P < 0.001), but there was no difference for advanced neoplasia. If endoscopists find these data convincing, they should trial these techniques separately because each technique may have a different impact.