[Ultrastructure of macrophages in the developing dermis++ and in the focus of aseptic inflammation in rats]

By means of the planimetry and stereometry methods ultrastructural peculiarities of macrophages in the developing dermis++ and in the focus of a subacute experimental inflammation have been investigated. Quantitative characteristics of various types of macrophages are presented. The part of macrophages of various types changes depending on age of the animal or on time of the experimental inflammation. Presence of a strong positive correlation between development of the lysosomal apparatus in ontogenesis and activity of the macrophage surface is stated. In the inflammatory focus this correlation is disturbed and sometimes it changes into a negative one. During the differentiation process of macrophages the synthesis and differentiation apparatuses are the first to form and then lysosomes. It is connected with the fact that the synthesis and secretion apparatuses are necessary for lysosomal formation, as well as for secretory function of macrophages.