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Amnesia01:13

Amnesia

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Amnesia is a condition marked by long-term memory loss, which impairs the ability to recall past events or create new memories.
The severity and duration of memory loss vary depending on the type and underlying cause. Amnesia is classified into two main types: retrograde and anterograde.
Retrograde amnesia is marked by the loss of memories formed before the onset of the condition. Patients may recall distant past events but often forget those occurring shortly before the incident.
Anterograde...
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Traumatic Memory01:20

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Emotionally traumatic events often lead to memories that are exceptionally vivid and enduring, sometimes persisting with remarkable clarity throughout an individual's life. A classic example of this phenomenon is a person who survives a car accident. Even years later, they may recall every detail of the event with startling accuracy — the screeching of the tires, the jarring impact, and the acrid smell of burning rubber. Such vividness contrasts sharply with how an individual...
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Dissociative Amnesia01:21

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Dissociative amnesia is a complex psychological condition that manifests as an inability to recall personal information, often tied to traumatic or stressful events. Unlike general amnesia, individuals with this condition retain the ability to perform routine activities and procedural tasks, such as operating a phone or navigating public transportation, yet experience profound gaps in autobiographical memory. These lapses may encompass significant life events, such as suicide attempts or...
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Interference and Decay01:16

Interference and Decay

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Forgetting is a complex cognitive phenomenon influenced by several factors, among which interference and decay are particularly prominent. These processes explain why individuals often struggle to retrieve specific information from memory, leading to lapses in recall that can be observed in everyday situations.
Interference occurs when competing memories hinder the retrieval of particular information. It can be classified into two types: proactive and retroactive interference. Proactive...
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Forgetting01:21

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Forgetting is an intrinsic aspect of human memory, characterized by the gradual loss or inaccessibility of information over time. Hermann Ebbinghaus, a pioneering psychologist, extensively studied this phenomenon and formulated the forgetting curve. This curve illustrates that memory loss occurs rapidly immediately after learning and then decelerates over time. Several mechanisms contribute to forgetting, including encoding failure, storage decay, retrieval failure, and interference.
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Higher Mental Functions of Brain: Learning and Memory01:26

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Memory is one of the most vital higher mental functions of the brain. Memory is closely related to learning because it enables us to retain information and experiences from our past to use them in our present life. It also helps us to remember facts, events, and skills, such as riding a bike or swimming. There are two types of memory — declarative memory, which involves memorizing facts or events, and procedural memory, which enables us to remember how to do something like writing or...
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Updated: Dec 26, 2025

A Prediction Error-driven Retrieval Procedure for Destabilizing and Rewriting Maladaptive Reward Memories in Hazardous Drinkers
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Factors determining recurrence in transient global amnesia.

Rebecca Tynas1, Peter K Panegyres2,3

  • 1The University of Western Australia, Nedlands, Australia.

BMC Neurology
|March 8, 2020
PubMed
Summary

Transient global amnesia (TGA) recurrence may be predicted by depression, prior head injury, and family history of dementia. These factors are more significant than diffusion-weighted imaging (DWI) lesions in the hippocampus.

Keywords:
DementiaDiffusion-weighted imagingRecurrentRisk factorsTransient global amnesia

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Area of Science:

  • Neurology
  • Neuroscience

Background:

  • The exact causes of transient global amnesia (TGA) are still unknown, with potential links to ischemia, migraines, or epilepsy.
  • Understanding TGA's etiology and recurrence factors is crucial for patient management.

Purpose of the Study:

  • To identify risk factors contributing to TGA.
  • To determine prognostic factors associated with TGA recurrence.

Main Methods:

  • Prospective evaluation of 93 TGA patients from 2004 to 2016.
  • Analysis of clinical history, family history, and magnetic resonance diffusion-weighted imaging (DWI).

Main Results:

  • Physical activities (Valsalva-like maneuvers) and emotional stress were common triggers.
  • Head injury, depression, and family history of dementia were linked to TGA recurrence.
  • DWI lesions in the hippocampus were observed in 24 patients but not significantly associated with outcomes.

Conclusions:

  • Depression, previous head injury, and family history of dementia are potential predictors of TGA recurrence.
  • DWI findings did not correlate with recurrence or long-term cognitive impairment.