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Related Concept Videos

Attention-Deficit/Hyperactivity Disorder01:30

Attention-Deficit/Hyperactivity Disorder

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Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by persistent inattention, hyperactivity, and impulsivity. It affects approximately 5-8% of children globally, with around 60-70% of cases persisting into adulthood. ADHD has significant implications for educational attainment, social interactions, and occupational success.
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings....
659

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Related Experiment Video

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Dynamic Inter-subject Functional Connectivity Reveals Moment-to-Moment Brain Network Configurations Driven by Continuous or Communication Paradigms
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ADHD classification by dual subspace learning using resting-state functional connectivity.

Ying Chen1, Yibin Tang2, Chun Wang3

  • 1Key Laboratory of Underwater Acoustic Signal Processing of Ministry of Education, Southeast University, China; Department of Psychiatry and Translational Imaging, Columbia University & NYSPI, USA.

Artificial Intelligence in Medicine
|March 8, 2020
PubMed
Summary

This study introduces a new dual subspace classification algorithm for identifying Attention Deficit Hyperactivity Disorder (ADHD) using functional connectivity. The novel framework achieves high accuracy, improving ADHD diagnosis.

Keywords:
ADHDFeature selectionGraph LaplacianGraph embeddingSVM-RFESubspace learning

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Area of Science:

  • Neuroscience
  • Medical Imaging
  • Machine Learning

Background:

  • Attention Deficit Hyperactivity Disorder (ADHD) is a common neurobehavioral disorder in children.
  • Accurate identification of ADHD patients remains a significant challenge.

Purpose of the Study:

  • To develop an effective algorithm for accurate ADHD identification using resting-state functional connectivity (FC).
  • To enhance the stability and efficiency of dual subspace classification for ADHD diagnosis.

Main Methods:

  • A dual subspace classification algorithm was proposed, learning separate subspaces for ADHD and healthy control features.
  • A modified graph embedding measure enhanced intra-class relationships.
  • A binary hypothesis testing framework was introduced to improve dual subspace stability by selecting discriminative FCs.

Main Results:

  • The proposed method achieved approximately 90% accuracy on the ADHD-200 dataset using leave-one-out cross-validation.
  • Demonstrated significant performance improvement compared to existing machine learning and deep learning methods.

Conclusions:

  • The novel ADHD classification framework based on binary hypothesis testing and dual subspace learning offers a promising approach for accurate ADHD diagnosis.
  • The method shows high potential for clinical application in identifying ADHD.