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[New analgesically-active N'-acylated phenylpiperazines]
1Forschung der Asta Pharma AG, Frankfurt/Main.
Arzneimittel-Forschung
|November 1, 1988
Abstract:
Synthesis and pharmacodynamic properties of new analgesic active N'-acylated phenylpiperazines are described. 1-(3-Cyclohexyl-1-oxo-propyl)-4-(2-ethoxyphenyl)-piperazine (D 16 120) possesses strong non-opiate antinociceptive activity showing high therapeutic margin with respect to undesired side effects and toxicity.