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Updated: Dec 26, 2025

Author Spotlight: Self-Assessment Protocol for Predicting Psoriatic Arthritis in Psoriasis Patients
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Author Spotlight: Self-Assessment Protocol for Predicting Psoriatic Arthritis in Psoriasis Patients

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[Intertriginous psoriasis].

C Thomas1, M Matthies1, B Homey1

  • 1Klinik für Dermatologie, Medizinische Fakultät, Heinrich-Heine-Universität, Moorenstr. 5, 40225, Düsseldorf, Deutschland.

Der Hautarzt; Zeitschrift Fur Dermatologie, Venerologie, Und Verwandte Gebiete
|March 8, 2020
PubMed
Summary
This summary is machine-generated.

Intertriginous psoriasis, affecting skin folds, causes significant patient distress. Ixekizumab shows promise as a systemic treatment for this challenging condition.

Keywords:
CandidaGenital psoriasisInterleukin-17A antagonistInverse psoriasisPsychological distress

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Area of Science:

  • Dermatology
  • Immunology
  • Psychodermatology

Background:

  • Intertriginous psoriasis is a variant of psoriasis characterized by inflammatory lesions in skin folds.
  • This condition can lead to shame, stigmatization, social isolation, and mental health issues in patients.
  • There is a lack of consensus on the definition and varying prevalence rates reported for intertriginous psoriasis.

Purpose of the Study:

  • To review the challenges in defining and managing intertriginous psoriasis.
  • To explore current and potential therapeutic options for intertriginous psoriasis.

Main Methods:

  • Literature review on intertriginous psoriasis definitions, prevalence, and treatment.
  • Analysis of existing data on topical and systemic treatment efficacy.

Main Results:

  • Therapeutic management of intertriginous psoriasis is challenging due to lesion location.
  • Mild symptoms are typically managed with topical corticosteroids or immunomodulators.
  • Encouraging efficacy data exists for ixekizumab, suggesting its potential as a systemic treatment.

Conclusions:

  • Intertriginous psoriasis presents unique diagnostic and therapeutic challenges.
  • Ixekizumab demonstrates potential as an effective systemic therapy, offering a new treatment avenue.