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Related Concept Videos

Inflammatory Bowel Disease I: Ulcerative Colitis01:27

Inflammatory Bowel Disease I: Ulcerative Colitis

773
Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
773
Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

848
Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
848
Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

698
Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
698
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy01:30

Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy

565
Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
565
Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

365
Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
365
Irritable Bowel Syndrome I: Introduction01:17

Irritable Bowel Syndrome I: Introduction

847
Irritable Bowel Syndrome (IBS) is characterized by functional disturbances in the gastrointestinal system, presenting a cluster of symptoms without evident structural or biochemical abnormalities. It primarily affects the large intestine and may cause abdominal pain, bloating, excessive gas, diarrhea, constipation, or both.
IBS is a chronic condition that can persist over a long period or recur frequently.
The pathogenesis of IBS involves a complex interplay of the following factors:
Altered...
847

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Related Experiment Video

Updated: Dec 26, 2025

A Murine Model of Fetal Exposure to Maternal Inflammation to Study the Effects of Acute Chorioamnionitis on Newborn Intestinal Development
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[IBD and pregnancy: From conception to birth].

A Foulon1, J Chevreau1, C Yzet2

  • 1Centre de gynécologie-obstétrique, CHU Amiens-Picardie, 1, rue du Professeur-Christian-Cabrol, 80054 Amiens, France.

Gynecologie, Obstetrique, Fertilite & Senologie
|March 8, 2020
PubMed
Summary

Inflammatory Bowel Diseases (IBD) management during pregnancy is crucial. Well-controlled IBD allows for safe pregnancy and delivery, with most treatments being compatible with breastfeeding.

Keywords:
Crohn diseaseFertilityFertilitéGrossesseMaladie de CrohnPregnancyRectocolite hémorragiqueUlcerative colitis

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Area of Science:

  • Gastroenterology
  • Reproductive Medicine
  • Obstetrics

Background:

  • Inflammatory Bowel Diseases (IBD) commonly affect individuals of reproductive age.
  • Patient misinformation can lead to infertility and poor pregnancy management in IBD patients.

Purpose of the Study:

  • To review the influence of IBD on pregnancy and vice versa across gestational stages.
  • To provide guidance based on current literature for managing IBD during pregnancy.

Main Methods:

  • Literature review of current scientific publications.
  • Analysis of the impact of IBD activity on fertility and pregnancy outcomes.
  • Evaluation of IBD treatment compatibility with pregnancy and breastfeeding.

Main Results:

  • IBD activity is a key factor; well-controlled IBD does not increase pregnancy risks.
  • Most IBD medications, excluding thalidomide and methotrexate, are safe during pregnancy and breastfeeding.
  • Optimal flare management is essential.
  • Vaginal delivery is generally safe, except with active anoperineal lesions.
  • Cesarean section should be considered for patients with ileal pouch-anal anastomosis.

Conclusions:

  • Maintaining controlled IBD is vital for successful pregnancy outcomes.
  • Appropriate medication selection and flare management are critical for pregnant IBD patients.
  • Delivery mode should be individualized based on IBD activity and surgical history.