Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Causality in Epidemiology01:21

Causality in Epidemiology

1.4K
Causality or causation is a fundamental concept in epidemiology, vital for understanding the relationships between various factors and health outcomes. Despite its importance, there's no single, universally accepted definition of causality within the discipline. Drawing from a systematic review, causality in epidemiology encompasses several definitions, including production, necessary and sufficient, sufficient-component, counterfactual, and probabilistic models. Each has its strengths and...
1.4K
Hardy-Weinberg Principle01:49

Hardy-Weinberg Principle

75.8K
Diploid organisms have two alleles of each gene, one from each parent, in their somatic cells. Therefore, each individual contributes two alleles to the gene pool of the population. The gene pool of a population is the sum of every allele of all genes within that population and has some degree of variation. Genetic variation is typically expressed as a relative frequency, which is the percentage of the total population that has a given allele, genotype or phenotype.
75.8K
Genetics of Speciation02:16

Genetics of Speciation

20.7K
Speciation is the evolutionary process resulting in the formation of new, distinct species—groups of reproductively isolated populations.
20.7K
Introduction to Epidemiology01:26

Introduction to Epidemiology

1.5K
Epidemiology, known as the cornerstone of public health, involves studying the distribution and determinants of health-related events in defined populations and applying these insights to control health issues. This is essential for understanding how diseases spread, identifying populations at greater risk, and implementing measures to control or prevent outbreaks. Epidemiology addresses not only infectious diseases but also non-communicable conditions like cancer and cardiovascular disease,...
1.5K
Limits to Natural Selection01:38

Limits to Natural Selection

33.8K
Organisms that are well-adapted to their environment are more likely to survive and reproduce. However, natural selection does not lead to perfectly adapted organisms. Several factors constrain natural selection.
33.8K
Evolutionary Psychology01:20

Evolutionary Psychology

829
Evolutionary psychology explores the origins of human behavior and mental processes by framing them within the context of natural selection, a theory famously propounded by Charles Darwin. This field asserts that many behaviors common across human societies — ranging from instinctive fear reactions to complex social interactions — arose as evolutionary adaptations. These adaptations enhanced the survival and reproductive success of our ancestors, thereby becoming embedded in the...
829

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A comparison of alternative vaccination strategies for protecting those vulnerable to illness, hospitalization, or death upon infection with SARS-CoV-2.

Journal of theoretical biology·2026
Same author

The adaptive plasticity of temperate phage <i>λ</i>.

Virus evolution·2026
Same author

Social cues drive the evolution of plastic pathogen virulence in spatially and temporally variable environments.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same author

Evolution of a trait distributed over a large fragmented population: propagation of chaos meets adaptive dynamics.

Journal of mathematical biology·2026
Same author

The interplay between migration and selection on the dynamics of pathogen variants.

Journal of the Royal Society, Interface·2026
Same author

Temperate phage evolve to integrate host stress and quorum signals in lysis-lysogeny decisions.

PLoS biology·2026

Related Experiment Video

Updated: Dec 26, 2025

Following the Dynamics of Structural Variants in Experimentally Evolved Populations
04:52

Following the Dynamics of Structural Variants in Experimentally Evolved Populations

Published on: February 3, 2023

1.3K

The Price equation and evolutionary epidemiology.

Troy Day1,2, Todd Parsons3, Amaury Lambert3

  • 1Department of Mathematics and Statistics, Queen's University, Jeffery Hall, Kingston, Ontario, Canada K7L 3N6.

Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences
|March 10, 2020
PubMed
Summary

The Price equation models disease evolution in continuous time. Demographic stochasticity in small populations weakens selection on transmission and strengthens selection on virulence, potentially lowering overall virulence.

Keywords:
demographic stochasticityeco-evolutionary feedbackfitness variancegenetic driftpathogen evolutionvirulence

More Related Videos

Quantifying Fitness Costs in Transgenic Aedes aegypti Mosquitoes
09:41

Quantifying Fitness Costs in Transgenic Aedes aegypti Mosquitoes

Published on: September 15, 2023

1.1K
Inoculating Anopheles gambiae Mosquitoes with Beads to Induce and Measure the Melanization Immune Response
08:24

Inoculating Anopheles gambiae Mosquitoes with Beads to Induce and Measure the Melanization Immune Response

Published on: January 12, 2017

8.3K

Related Experiment Videos

Last Updated: Dec 26, 2025

Following the Dynamics of Structural Variants in Experimentally Evolved Populations
04:52

Following the Dynamics of Structural Variants in Experimentally Evolved Populations

Published on: February 3, 2023

1.3K
Quantifying Fitness Costs in Transgenic Aedes aegypti Mosquitoes
09:41

Quantifying Fitness Costs in Transgenic Aedes aegypti Mosquitoes

Published on: September 15, 2023

1.1K
Inoculating Anopheles gambiae Mosquitoes with Beads to Induce and Measure the Melanization Immune Response
08:24

Inoculating Anopheles gambiae Mosquitoes with Beads to Induce and Measure the Melanization Immune Response

Published on: January 12, 2017

8.3K

Area of Science:

  • Evolutionary biology
  • Epidemiology
  • Mathematical modeling

Background:

  • The Price equation is a fundamental tool in evolutionary biology.
  • Its application to evolutionary epidemiology of infectious diseases is explored.
  • Previous models often did not account for continuous time or overlapping generations.

Purpose of the Study:

  • To adapt the Price equation for continuous-time models with overlapping generations.
  • To provide an epidemiological interpretation of the Price equation's terms for pathogen evolution.
  • To investigate the impact of demographic stochasticity on disease evolution.

Main Methods:

  • Derivation of a continuous-time Price equation.
  • Analysis of epidemiological interpretations of the equation's components.
  • Extension of the model to include demographic stochasticity in small populations.

Main Results:

  • The continuous-time Price equation offers a novel perspective on pathogen evolution.
  • Demographic stochasticity partitions evolutionary change naturally.
  • Stochasticity weakens selection on transmission rates and strengthens selection on mortality (virulence).

Conclusions:

  • The Price equation framework is valuable for understanding disease evolution, especially with demographic stochasticity.
  • Demographic stochasticity can lead to the evolution of lower virulence due to trade-offs with transmission.
  • This work provides a robust mathematical foundation for evolutionary epidemiology.