Intervention for Iliofemoral Deep Vein Thrombosis and May-Thurner Syndrome

Taufiq Salahuddin1, Ehrin J Armstrong2

  • 1Cardiology Section, Rocky Mountain Regional VA Medical Center, 1700 North Wheeling Street, Aurora, CO 80045, USA.

Insights

May-Thurner syndrome, or iliac vein compression, can lead to iliofemoral deep vein thrombosis (DVT). Catheter-directed treatments like thrombolysis and stenting offer procedural interventions for DVT and venous compression.

Area of Science:

  • Vascular Surgery
  • Interventional Radiology
  • Cardiovascular Medicine

Background:

  • May-Thurner syndrome (iliac vein compression) predisposes individuals to iliofemoral deep vein thrombosis (DVT).
  • Iliofemoral DVT frequently leads to postthrombotic syndrome, causing chronic venous insufficiency and reduced quality of life.
  • Venous hypertension is a key symptom associated with May-Thurner syndrome.

Purpose of the Study:

  • To review procedural interventions for iliofemoral deep vein thrombosis (DVT).
  • To discuss the management of May-Thurner syndrome (iliac vein compression).
  • To highlight the role of catheter-directed thrombolysis and stenting in treating these conditions.

Main Methods:

  • Review of procedural interventions for iliofemoral DVT and May-Thurner syndrome.
  • Focus on catheter-directed thrombolysis.
  • Emphasis on the application of stenting in managing venous outflow obstruction.

Main Results:

  • Procedural interventions, including thrombolysis and stenting, are effective in managing iliofemoral DVT.
  • These interventions address underlying iliac vein compression contributing to DVT.
  • Successful treatment can alleviate symptoms of venous hypertension and potentially prevent postthrombotic syndrome.

Conclusions:

  • Catheter-directed thrombolysis and stenting are valuable treatment options for iliofemoral DVT.
  • Addressing May-Thurner syndrome through these procedures can improve venous outflow and patient outcomes.
  • Interventional techniques offer a minimally invasive approach to managing complex venous conditions.

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