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Updated: Dec 26, 2025

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Insufficient laboratory monitoring and progressive multifocal leukoencephalopathy on fumaric acid ester therapy for

Peter Elsner1

  • 1Department of Dermatology, University Medical Center, Jena, Germany.

Journal Der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG
|March 10, 2020
PubMed
Abstract

No abstract available in PubMed .

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Therapeutic Drug Monitoring (TDM) is the clinical practice of measuring specific drug levels in a patient's blood or body tissues to manage and optimize therapy. TDM is crucial for drugs with narrow therapeutic windows, like warfarin and phenytoin, where incorrect doses can lead to treatment failure or severe side effects. This monitoring ensures the dosage administered is within a safe and effective range. The factors affecting therapeutic drug monitoring include:Patient-Specific Factors:a.
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