Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Redox-responsive ionic covalent organic framework films for hydroxide ion transport and tunable mechanical properties.

Chemical science·2026
Same author

Symmetry Breaking in Chemical Systems: Engineering Complexity Through Self-Organization and Marangoni Flows.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2025
Same author

Universities must move with the times: how six scholars tackle AI, mental health and more.

Nature·2025
Same author

Pollution source tracing and health impact of PM<sub>10</sub> elements using DN-PMF in sub-urban sites of the Indian Himalayan Region.

Environmental geochemistry and health·2025
Same author

Oxygen deficiency drives drastic pattern transition in algal bioconvection.

Soft matter·2025
Same author

Integrated mineral identification of PM<sub>10</sub> using XRD, ATR-FTIR and SEM-EDX techniques in Indo-Gangetic Plain (IGP) and Indo-Himalayan Region (IHR).

Environmental monitoring and assessment·2025

Related Experiment Video

Updated: Dec 26, 2025

Measurement of Extracellular Ion Fluxes Using the Ion-selective Self-referencing Microelectrode Technique
09:18

Measurement of Extracellular Ion Fluxes Using the Ion-selective Self-referencing Microelectrode Technique

Published on: May 3, 2015

14.3K

Measuring Cellular Ion Transport by Magnetoencephalography.

Sudhir Kumar Sharma1, Sauparnika Vijay2, Sangram Gore2

  • 1Engineering Division, New York University Abu Dhabi, PO Box 129188, Abu Dhabi, UAE.

ACS Omega
|March 10, 2020
PubMed
Summary

Magnetoencephalography (MEG) noninvasively measured magnetic fields from cellular ion transport. This technique shows potential for detecting cancer by observing ion channel activity and ionic flux.

More Related Videos

Application of Electrophysiology Measurement to Study the Activity of Electro-Neutral Transporters
11:51

Application of Electrophysiology Measurement to Study the Activity of Electro-Neutral Transporters

Published on: February 3, 2018

7.4K
Double-barreled and Concentric Microelectrodes for Measurement of Extracellular Ion Signals in Brain Tissue
11:08

Double-barreled and Concentric Microelectrodes for Measurement of Extracellular Ion Signals in Brain Tissue

Published on: September 5, 2015

14.2K

Related Experiment Videos

Last Updated: Dec 26, 2025

Measurement of Extracellular Ion Fluxes Using the Ion-selective Self-referencing Microelectrode Technique
09:18

Measurement of Extracellular Ion Fluxes Using the Ion-selective Self-referencing Microelectrode Technique

Published on: May 3, 2015

14.3K
Application of Electrophysiology Measurement to Study the Activity of Electro-Neutral Transporters
11:51

Application of Electrophysiology Measurement to Study the Activity of Electro-Neutral Transporters

Published on: February 3, 2018

7.4K
Double-barreled and Concentric Microelectrodes for Measurement of Extracellular Ion Signals in Brain Tissue
11:08

Double-barreled and Concentric Microelectrodes for Measurement of Extracellular Ion Signals in Brain Tissue

Published on: September 5, 2015

14.2K

Area of Science:

  • Biophysics
  • Cell Biology
  • Medical Imaging

Background:

  • Cellular ion transport generates magnetic fields.
  • Magnetoencephalography (MEG) is a noninvasive brain imaging technique.
  • Ion channel activity is linked to cancer development.

Purpose of the Study:

  • To investigate the use of MEG for detecting cellular ion transport.
  • To explore the potential of MEG as a noninvasive cancer detection method.

Main Methods:

  • Measured magnetic fields from HeLa, HEK293, and H9c2(2-1) cells using MEG.
  • Induce ion influx using ionomycin and capsaicin.
  • Correlated MEG signals with confocal fluorescence microscopy.

Main Results:

  • Observed magnetic field changes consistent with calcium (Ca2+) influx upon stimulation.
  • Confirmed MEG signals originate from cellular ion transport.
  • Demonstrated that blocking ion channels abolished both magnetic and fluorescent signals.

Conclusions:

  • MEG can noninvasively detect cellular ion transport.
  • The findings suggest MEG's potential as a novel method for cancer detection.
  • Further research into ion channel dynamics could advance cancer diagnostics.