Unintentional Pediatric Poisoning Exposures in an Emergency Department: A Comparison of Poison Control Center

Amberly R Johnson, Casey R Tak, Michael Mundorff1

  • 1Department of Systems Improvement, Primary Children's Hospital, Intermountain Healthcare.

Insights

Pediatric emergency department visits for unintentional poisoning show disparities in poison control center (PCC) utilization. Educational outreach is needed to ensure optimal PCC services for all patients and caregivers.

Area of Science:

  • Pediatric Emergency Medicine
  • Toxicology
  • Public Health

Background:

  • Unintentional poisoning is a common reason for pediatric emergency department (ED) visits.
  • Poison control centers (PCCs) provide crucial guidance for poisoning exposures.
  • Understanding referral patterns to the ED is essential for optimizing PCC utilization.

Purpose of the Study:

  • To compare the demographics and clinical characteristics of pediatric patients with unintentional poisoning exposures referred by a PCC versus those who self-referred to the ED.
  • To identify factors influencing self-referral versus PCC referral for pediatric poisoning cases.

Main Methods:

  • Retrospective query of a pediatric hospital's electronic data warehouse (October 2014-September 2015).
  • Identification of patients aged 18 years and younger with unintentional poisoning using ICD-9-CM codes.
  • Classification of referrals as PCC-referred or self-referred based on medical records.
  • Descriptive statistics and logistic regression to analyze demographic and clinical characteristics associated with referral type.

Main Results:

  • Of 705 patients, 84.4% were self-referred; PCC-referred patients were more likely to be white and have commercial insurance.
  • Pharmaceutical exposures (71.9%) and chemical exposures (14.0%) were most common in PCC-referred cases.
  • Foreign body ingestions (54.3%) were most common in self-referred cases.
  • Age, insurance status, and exposure type were significant predictors of self-referral.

Conclusions:

  • Significant disparities exist in poison control center utilization among pediatric patients presenting to the ED for unintentional poisoning.
  • Differences in utilization are observed across age groups, racial identification, and types of poison exposure.
  • Targeted educational outreach is necessary for patients, caregivers, and healthcare professionals to improve PCC service utilization.
Abstract

Related Concept Videos

Prevention of Further Absorption of Poison01:14

Prevention of Further Absorption of Poison

In cases of acute poisoning, the primary objective is to prevent further absorption of the toxic substance into the body. Immediate interventions using various decontamination techniques targeting the gastrointestinal (GI) tract can achieve this. Decontamination is crucial to prevent poison from entering the systemic circulation, which involves washing affected areas with water and mild soap and removing contaminated clothing. Once external decontamination is done, attention must be turned to...
1.1K
Anticholinesterase Agents: Poisoning and Treatment01:26

Anticholinesterase Agents: Poisoning and Treatment

Anticholinesterases, also known as cholinesterase inhibitors, work by blocking the breakdown of acetylcholine, leading to its accumulation in the synaptic cleft. This accumulation indirectly enhances both muscarinic and nicotinic actions. These agents are classified as reversible or irreversible based on their mechanism of action.     
Irreversible agents form a strong bond with the cholinesterase enzyme, making it inactive. The breakdown of the phosphorylated enzyme is...
1.4K
Enhanced Elimination of Poison01:26

Enhanced Elimination of Poison

Poison can be effectively removed from the gastrointestinal (GI) tract through various decontamination procedures.
Antidotes serve a crucial role in counteracting the effects of poison by inhibiting enzymes responsible for producing harmful drug metabolites. In some cases, these toxic metabolites can be neutralized by endogenous cosubstrates, which are maintained at specific concentrations to prevent interaction with cellular macromolecules and subsequent cell death.
Renal excretion is the...
791
Drug Dosing: Infants and Children01:29

Drug Dosing: Infants and Children

Pediatric patient dosages diverge from adults due to disparities in body surface area, total body water, and extracellular fluid per kilogram of body weight. The dosing regimen considers the variations in pharmacokinetics and pharmacology across distinct age groups, encompassing preterm newborns, infants, young children, older children, and adolescents. Calculation of pediatric patient doses is predicated on determining body surface area, which exhibits a superior correlation with the child's...
185
Pharmacovigilance01:19

Pharmacovigilance

Post-marketing surveillance is a critical component of pharmaceutical regulation, often uncovering unanticipated adverse drug reactions (ADRs) once a drug is widely used over an extended period.
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...
1.5K
Pharmacokinetics in Pediatric Patients: Drug Excretion01:26

Pharmacokinetics in Pediatric Patients: Drug Excretion

In pediatric medicine, understanding the renal function and drug elimination nuances is crucial for administering safe and effective treatments. Newborns, in particular, display markedly slower renal functions than adults, profoundly affecting how drugs are cleared from their bodies. This slower drug clearance requires clinicians to extend the dosing intervals for many medications to prevent drug accumulation and toxicity while ensuring therapeutic efficacy.One key area where these adjustments...
156