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Microcomputer-assisted univariate survival data analysis using Kaplan-Meier life table estimators.

N Campos-Filho1, E L Franco

  • 1Epidemiology and Biostatistics Unit, Ludwig Institute for Cancer Research, Sao Paulo, Brazil.

Computer Methods and Programs in Biomedicine
|November 1, 1988
PubMed
Summary
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KMSURV is a microcomputer program for survival data analysis, aiding clinical trials and epidemiological studies. It provides Kaplan-Meier estimates, survival times, and comparative statistical tests with high-resolution plots.

Area of Science:

  • Biostatistics
  • Medical Informatics
  • Epidemiology

Background:

  • Survival data analysis is crucial for clinical trials and epidemiological research.
  • Existing mainframe solutions may not fully leverage microcomputer capabilities.

Purpose of the Study:

  • To introduce KMSURV, a microcomputer program for exploratory univariate statistical analysis of survival data.
  • To facilitate the evaluation of clinical trials and retrospective epidemiological studies.

Main Methods:

  • Utilizes Kaplan-Meier's product-limit estimators for survivorship function S(t) calculations.
  • Provides life-table-like information and summary measures of average survival times.
  • Performs two non-parametric tests for comparing survival distributions.

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Main Results:

  • KMSURV generates report-quality, high-resolution plots of S(t) estimates for comparative analyses.
  • The program efficiently uses the interactive microcomputing environment.
  • Offers comprehensive univariate statistical analysis for survival data.

Conclusions:

  • KMSURV is a valuable tool for survival data analysis on microcomputers.
  • The program enhances the evaluation of clinical trials and epidemiological studies.
  • Its design optimizes the use of interactive microcomputing environments.