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Related Experiment Video

Updated: Dec 26, 2025

Frailty Assessment in an Aging Mouse Model
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Moving Towards Common Data Elements and Core Outcome Measures in Frailty Research.

J Muscedere1, J Afilalo, I Araujo de Carvalho

  • 1John Muscedere, Queen's University and Kingston General Hospital, Canada,

The Journal of Frailty & Aging
|March 10, 2020
PubMed
Summary

Frailty research needs standardized data. Common data elements (CDEs) and core outcome measures (COMs) will improve evidence-based care for aging populations globally.

Keywords:
Frailtycommon data elementscore outcome measures

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Area of Science:

  • Gerontology and Public Health
  • Clinical Trial Methodology
  • Evidence-Based Practice

Background:

  • Global aging populations are increasing frailty prevalence, necessitating evidence-based care.
  • Current frailty research lacks high-quality evidence due to inconsistent methodologies and reporting.
  • Variations in population descriptions, assessment tools, and outcomes hinder research interpretation and implementation.

Purpose of the Study:

  • To address the need for standardized data in frailty research.
  • To catalyze the development and adoption of common data elements (CDEs) and core outcome measures (COMs) for frailty studies.
  • To outline a path forward for establishing consensus on CDEs and COMs in frailty research.

Main Methods:

  • Convened an international expert group under the Canadian Frailty Network (CFN).
  • Examined current frailty evidence and learned from other CDEs and COMs initiatives.
  • Discussed specific considerations for frailty CDEs and COMs and identified steps for consensus.

Main Results:

  • Identified critical gaps in frailty research methodology and data standardization.
  • Highlighted the importance of CDEs and COMs for improving the quality and comparability of frailty research.
  • Established a consensus statement on the necessity and future direction for CDEs and COMs in frailty.

Conclusions:

  • Standardization through CDEs and COMs is crucial for advancing frailty science.
  • Implementing standardized elements will enhance the reliability and generalizability of frailty research findings.
  • A collaborative, consensus-driven approach is required to develop and implement frailty-specific CDEs and COMs.