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Cervical cancer burden in Latin America and the Caribbean: Where are we?
Sophie Pilleron1, Citadel J Cabasag2, Jacques Ferlay2
1Prevention and Implementation Group, Section of Early Detection and Prevention, International Agency for Research on Cancer, Lyon, France.
Insights
Cervical cancer incidence and mortality rates in Latin America and the Caribbean are decreasing, but remain above the elimination threshold. Continued political and economic commitment is crucial for achieving cervical cancer elimination.
Area of Science:
- Oncology
- Public Health
- Epidemiology
Background:
- The World Health Organization (WHO) initiated a global strategy for cervical cancer elimination in May 2018.
- Cervical cancer remains a significant public health challenge in the Latin America and Caribbean (LAC) region.
Purpose of the Study:
- To monitor progress towards cervical cancer elimination in the LAC region.
- To analyze cervical cancer incidence and mortality trends from 2008 to 2018.
Main Methods:
- Utilized GLOBOCAN 2018, Cancer Incidence in Five Continents Series, and WHO Mortality Database.
- Estimated 2018 cervical cancer incidence and mortality rates (age-standardized rates - ASRs).
- Analyzed trends and calculated average annual percentage change over 10 years for various age groups.
Main Results:
- In 2018, an estimated 56,000 new cervical cancer cases and 28,000 deaths occurred in the LAC region.
- Cervical cancer incidence and mortality rates showed a decreasing trend over the past decade.
- Rates in most LAC countries/territories exceed the 4 per 100,000 elimination threshold.
Conclusions:
- While trends are encouraging, substantial political and economic commitment is needed to achieve cervical cancer elimination in LAC.
- Population-based cancer registries are essential for effective monitoring of the elimination initiative.
Abstract:
In May 2018, the World Health Organization (WHO) called for the elimination of cervical cancer. To monitor this initiative, we examined cervical cancer incidence and mortality in the Latin America and Caribbean (LAC) region using GLOBOCAN 2018, Cancer Incidence in Five Continents Series, and the WHO Mortality Database. We estimated the number of cases and age-standardized rates (ASRs) for cervical cancer incidence and mortality for 2018. We also presented the ASRs for recorded cervical cancer incidence from the period 2008 to 2012. We calculated annual rates and analyzed trends in cervical cancer incidence and mortality for all ages combined and for the following age groups: 0-29, 30-49, 50-64 and 65+. Finally, we calculated the estimated average annual percentage change in incidence and mortality rates for the past 10 years. In 2018, an estimated 56,000 new cervical cancer cases and 28,000 cervical cancer deaths occurred among women in LAC with great variations between subregions and countries/territories. Overall, trends in cervical cancer incidence and mortality have decreased over the past decade; however, the rates are still above the elimination threshold of 4 per 100,000 in most LAC countries/territories. Despite the encouraging trends observed, achieving the elimination of cervical cancer in the region still requests substantial political commitment and economic effort. Population-based cancer registries are critical in monitoring the elimination initiative.
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