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A systematic review of prevention and treatment of infantile colic

Anders Hjern1,2,3, Kristin Lindblom4, Antonia Reuter5

  • 1Sachs' Children and Youth hospital, Stockholm, Sweden.

Acta Paediatrica (Oslo, Norway : 1992)
|March 10, 2020
PubMed

Insights

Lactobacillus reuteri DSM 17938 shows promise for treating infantile colic by reducing crying duration. Acupuncture is ineffective, and more research is needed on parental support strategies.

Area of Science:

  • Pediatrics
  • Gastroenterology
  • Evidence-based medicine

Background:

  • Infantile colic is a common condition affecting infants, characterized by prolonged and inconsolable crying.
  • Effective interventions for infantile colic are sought by healthcare providers and parents.

Purpose of the Study:

  • To systematically review and evaluate the evidence for interventions aimed at treating infantile colic.

Main Methods:

  • A systematic review of randomized controlled trials (RCTs) and meta-analyses published between 2007-2017.
  • Studies included at least 20 infants per group and were assessed using GRADE criteria.

Main Results:

  • Moderately strong evidence supports Lactobacillus reuteri DSM 17938 in shortening infant crying duration.
  • Four RCTs found acupuncture to have no significant effect on crying duration.
  • Crying duration naturally declines over time in infants, regardless of treatment.

Conclusions:

  • Lactobacillus reuteri DSM 17938 is a promising treatment for infantile colic, though further population studies are recommended.
  • Acupuncture is not an effective intervention for infantile colic.
  • Knowledge gaps exist regarding systematic support strategies for parents managing infantile colic.
Abstract

Keywords:
acupuncturecolicexcessive cryinginfantinfantile colicprobiotics

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