Efficient Cascade Resonance Energy Transfer in Dynamic Nanoassembly for Intensive and Long-Lasting Multicolor...

Area of Science:

• Supramolecular Chemistry
• Materials Science
• Biotechnology

Background:

• Chemiluminescence (CL) systems typically produce short-lived, single-color emissions, limiting their use in advanced applications.
• Achieving long-lasting, multicolor CL in aqueous solutions is a significant challenge for biological and imaging fields.

Purpose of the Study:

• To develop a novel strategy for highly efficient, long-lasting multicolor chemiluminescence in aqueous solutions.
• To create a dynamic nanoassembly system utilizing β-cyclodextrin (β-CD) for enhanced cascade Förster resonance energy transfer (FRET).

Main Methods:

• Fabrication of dynamic nanoassemblies using β-cyclodextrin (β-CD), CL reagents, and fluorophores in aqueous solution.
• Utilizing cascade FRET within the nanoassembly to achieve efficient energy transfer (up to 92%).
• Employing hydroxypropyl methylcellulose and Ca(OH)₂ to control diffusion and pH for sustained CL reactions.

Main Results:

• Intensive multicolor CL emission with tunable wavelengths (410-610 nm) was achieved.
• The developed system demonstrated long-lasting CL visible to the naked eye for over 20 hours.
• The multicolor CL systems were successfully applied to create transformable 2D multicolor codes for encryption.

Conclusions:

• The dynamic nanoassembly strategy offers a highly efficient method for generating long-lasting multicolor CL in aqueous solutions.
• This approach significantly expands the potential applications of CL in bioassays, imaging, and security.
• The system represents a significant advancement over traditional flash-type CL systems.