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A Mouse Distraction Osteogenesis Model

A Mouse Distraction Osteogenesis Model

Published on: November 14, 2018

Macrodontia Associated with Mandibular Distraction Osteogenesis.

Mark E Herring¹, Catherine Lee², Jesse Taylor³

¹Dr. Herring is a pediatric dentist in private practice, Cary and Cameron, N.C., USA.

Journal of Dentistry for Children (Chicago, Ill.)

|March 11, 2020

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Mandibular distraction osteogenesis (MDO) in infants can cause dental anomalies. This case highlights unusual macrodontia of a primary molar, likely due to distraction histogenesis during MDO, emphasizing careful surgical planning.

Area of Science:

Pediatric dentistry
Craniofacial surgery
Developmental biology

Background:

Pierre Robin sequence often causes infant airway obstruction.
Mandibular distraction osteogenesis (MDO) surgically elongates the mandible to improve airway.
MDO in infants carries risks, including dental complications near osteotomy sites.

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Last Updated: Dec 26, 2025

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