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Related Experiment Videos

Preliminary data on a field study with a new hypo-allergic formula.

Y Vandenplas1, M Deneyer, L Sacre

  • 1Academic Children's Hospital, Free University of Brussels, Belgium.

European Journal of Pediatrics
|December 1, 1988
PubMed
Summary

A new hypoallergenic formula (HAF) prevented atopic manifestations in at-risk newborns. Infants fed HAF exclusively showed no symptoms, while others on adapted formula (AdFo) or breast milk experienced fewer issues with HAF introduction.

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Area of Science:

  • Pediatrics
  • Allergy and Immunology
  • Neonatal Nutrition

Background:

  • Infants at risk for atopy often develop manifestations due to cow's milk proteins.
  • Early identification and intervention are crucial for managing infant atopy.

Purpose of the Study:

  • To evaluate the efficacy of a new hypoallergenic formula (HAF) in preventing atopic manifestations in high-risk newborns.
  • To compare the incidence of atopy in infants fed HAF, adapted formula (AdFo), or breast milk.

Main Methods:

  • A study involving five groups of 15 newborns with a positive family history of atopy.
  • Infants were fed either AdFo, breast milk, or HAF for a 4-month period.
  • Monitoring for the appearance and disappearance of atopic symptoms.

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Main Results:

  • No infants exclusively fed HAF from birth developed atopic symptoms.
  • 1 out of 15 breast-fed infants and 18 out of 45 infants fed AdFo showed atopic manifestations.
  • All 18 infants on AdFo with symptoms improved upon switching to HAF.

Conclusions:

  • The hypoallergenic formula (HAF) shows significant promise in preventing cow's milk-related atopy in at-risk infants.
  • Further research with larger populations and double-blind studies is warranted to confirm these findings.