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Guided walking reduces blood pressure in hypertensive sedentary subjects including those with resistant hypertension
Simona Mandini1, Francesco Conconi2, Elisa Mori2
1Center for Exercise Science and Sport, University of Ferrara, Ferrara, Italy. mndsmn@unife.it.
Insights
Guided walking significantly reduces systolic blood pressure in hypertensive individuals, including those with resistant hypertension. This 1-year program demonstrated clinically relevant blood pressure lowering effects through habitual walking.
Area of Science:
- Cardiology
- Exercise Physiology
- Public Health
Background:
- Hypertension is a global health concern, often requiring multiple medications.
- Resistant hypertension is defined as hypertension poorly responsive to medications.
- Previous research indicated guided walking reduces systolic blood pressure in hypertensive subjects.
Purpose of the Study:
- To assess the impact of a 1-year guided walking program on blood pressure.
- To evaluate effects in sedentary hypertensive subjects, including those with resistant hypertension.
- To compare outcomes between subjects with and without blood pressure medication therapy.
Main Methods:
- 259 sedentary hypertensive subjects (systolic pressure ≥130 mmHg) were enrolled.
- Subjects were divided into groups with and without antihypertensive medication (≥3 drugs including diuretics).
- Measurements included blood pressure, weight, BMI, waist circumference, and walking speed over 1 year.
Main Results:
- A significant decrease in systolic blood pressure (P < 0.0001) was observed in both groups after 1 year.
- The reduction in systolic pressure was significantly greater in subjects on medication therapy (P < 0.0001).
- Systolic blood pressure decrease was directly proportional to baseline values; diastolic pressure also decreased significantly.
Conclusions:
- Habitual walking can lead to clinically significant blood pressure reductions.
- Guided walking is effective for sedentary hypertensive individuals, including those with resistant hypertension.
- Exercise interventions like walking offer a viable strategy for managing hypertension.
Abstract:
Hypertension poorly responsive to medications is defined resistant hypertension. We have previously shown that 1-year of guided walking is followed by highly significant reduction of systolic blood pressure in hypertensive subjects. Aim of this study was to assess the effect of a 1-year of guided walking on the blood pressure of sedentary hypertensive subjects including patients with resistant hypertension. Two hundred and fifty-nine sedentary subjects with systolic pressure ≥130 mmHg were subdivided in a group without blood pressure medications and in a group taking three or more antihypertensive drugs, including diuretics. Blood pressure, body weight, body mass index, waist circumference, and walking speed were determined at enrollment and after 1-year of walking, supervised by exercise physiologists. At baseline, systolic pressure was significantly higher in the subjects under therapy (144.6 ± 12.2 vs. 140.2 ± 10.7). Two hundred and three subjects (124 without and 79 with therapy) completed the program. During the 1-year program each subject walked ~220 h. After 1-year a significant decrease (P < 0.0001) of systolic pressure was observed in both groups. The decrease was significantly higher (P < 0.0001) in the subjects under therapy. The decrease of systolic pressure was directly proportional to baseline values. Diastolic blood pressure decreased significantly in both groups. In conclusion, habitual walking may lead to clinically significant reductions of blood pressure in therapy resistant hypertensive subjects.
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