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Microvascular circulatory changes in the lower extremities after reconstructive vascular surgery for intermittent
P Rørdam1, L Simonsen, R Jelnes
1Department of Surgery H, Gentofte Hospital, Denmark.
European Journal of Vascular Surgery
|August 1, 1988
Summary
Reconstructive vascular surgery improved blood flow in the lower extremities, particularly during sleep, and enhanced the vasoconstrictor response in patients with intermittent claudication.
Area of Science:
- Vascular Surgery
- Physiology
- Blood Flow Dynamics
Background:
- Intermittent claudication significantly impairs lower extremity circulation.
- Reconstructive vascular surgery aims to restore blood flow and improve limb function.
Purpose of the Study:
- To investigate the circulatory changes in the lower extremities following reconstructive vascular surgery in patients with intermittent claudication.
Main Methods:
- Measurements included ankle systolic blood pressure, calf plethysmography, and resting blood flow (muscle and subcutaneous tissue) before and after surgery.
- Vasoconstrictor response (veno-arteriolar reflex) and nocturnal forefoot subcutaneous adipose tissue blood flow were also assessed.
Main Results:
- Significant increases in ankle systolic blood pressure and ankle index were observed post-surgery.
- No significant changes in daytime limb, muscle, or daytime forefoot subcutaneous blood flow were found.
- Nocturnal forefoot subcutaneous adipose tissue blood flow and vasoconstrictor response showed significant increases, which were maintained at 28 days post-operation.
Conclusions:
- Reconstructive vascular surgery effectively improves arterial blood pressure and enhances vasoconstrictor response in the lower extremities.
- Nocturnal subcutaneous adipose tissue blood flow in the forefoot significantly increases after surgery, indicating improved tissue perfusion during rest.