Related Experiment Video
Updated: Dec 26, 2025

A Method for Manipulating Blood Glucose and Measuring Resulting Changes in Cognitive Accessibility of Target Stimuli
Published on: August 12, 2016
Assessment of sugar-sweetened beverage consumption and weight change: a prospective cohort study
Patrick Mullie1,2,3, Philippe Autier1,4, Mathieu Boniol1,4
11International Prevention Research Institute, 95 Cours Lafayette, 69006 Lyon, France.
Background:
In prospective studies, sugar-sweetened beverages (SSB) have been associated with weight increase. However, most prospective studies examine changes in body weight over time according to amounts of SSB intake at baseline, generally without considering changes over time in SSB, energy intake and physical activity. The objective of the present study was to examine how SSB intakes influence changes in weight, according to the way SSB intakes are analysed.
Methods:
For a prospective cohort study with two nutritional assessments in time, 46 Flemish municipalities were selected by clustered random sampling. Within these municipalities, a random sample of men and women between 18 and 75 years of age was selected and invited to participate. In total, 562 middle-aged Belgian adults were tested in 2002 and 2012 for the same anthropometric, lifestyle, nutrition and physical activity parameters. The main outcome measured were weight changes from 2002 to 2012 were analysed according to various ways to parametrise SSB intakes in 2002 and changes in SSB, energy intake, and physical activity from 2002 to 2012.
Results:
In a multivariable model including age, sex, the best predictors of weight changes were the weight at baseline (P < 0.001), then the change in energy intake (p = 0.068). No association was found with SSB intake at baseline (P = 0.267) and the change in SSB intake (P = 0.130).
Conclusions:
Results of prospective studies on SSB intake and body weight depend much on the way SSB intakes are analysed, and on the inclusion of changes in energy intake and physical activity in analyses.
Related Concept Videos
Observational Studies
There are three types of observational studies – Prospective, retrospective, and cross-sectional.
Prospective Study
Prospective studies, also known as longitudinal or cohort studies, are carried out by collecting future data from groups sharing similar characteristics. One...
Study Designs in Epidemiology
Observational studies are those where the researcher does not intervene but rather observes natural variations. They include cross-sectional, cohort, and...
Bias in Epidemiological Studies

