Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Renal Corpuscle01:20

Renal Corpuscle

6.6K
The glomerulus and Bowman's capsule are two essential components of the nephron, which is the functional unit of the kidney. These microscopic structures play a critical role in the process of blood filtration to produce urine.
Glomerulus: Structure and Function
The glomerulus is a tiny, intricate network of capillaries located at the beginning of the nephron. It's enveloped by the Bowman's capsule and receives its blood supply from an afferent arteriole, which divides into numerous...
6.6K
Internal Anatomy of the Kidney01:12

Internal Anatomy of the Kidney

5.5K
The kidneys are essential organs in the human body, performing a myriad of tasks that maintain homeostasis and overall health.
Anatomical Position and Dimensions
The kidneys are retroperitoneal organs positioned against the posterior abdominal wall on either side of the spine, roughly between the twelfth thoracic and third lumbar vertebrae. Each kidney is typically 10-12 cm long, 5-6 cm wide, and 3-4 cm thick, weighing about 150 grams.
Renal Cortex
The outermost region of the kidney is the...
5.5K
Nephrons01:10

Nephrons

6.0K
The kidneys are intricate organs with millions of working units known as nephrons. Each nephron features two major structures: the renal corpuscle, which facilitates blood plasma filtration, and the renal tubule, which handles the glomerular filtrate. Blood supply is directly linked to the nephrons. The renal corpuscle consists of the glomerulus, a capillary network, and the Bowman's capsule, a double-walled epithelial structure that encases the glomerulus. The filtering of blood plasma...
6.0K
Kidney Structure01:45

Kidney Structure

74.1K
The kidneys are two large bean-shaped organs located in the upper abdomen. They filter the blood several times a day to remove toxins and rebalance water and electrolytes of the circulatory system via the renal veins. The kidneys receive blood directly from the heart via the renal arteries. These arteries enter the kidney at the hilum, the concave surface of the bean, where they branch and divide into smaller vessels and capillaries.
74.1K
Imaging Studies I: Kidney, Ureter, and Bladder Studies01:28

Imaging Studies I: Kidney, Ureter, and Bladder Studies

193
Kidney, Ureter, and Bladder (KUB) StudiesKidney, Ureter, and Bladder (KUB) studies are standard diagnostic imaging procedures used to assess the anatomy of the urinary system. They are commonly utilized for patients experiencing abdominal pain or urinary symptoms. By using a simple X-ray of the abdomen, KUB studies can reveal structural and pathological abnormalities within the kidneys, ureters, and bladder. These studies are particularly valuable in diagnosing kidney stones, urinary...
193
Renal Tubule and Collecting Duct01:24

Renal Tubule and Collecting Duct

2.8K
The renal tubule is divided into three parts: the proximal convoluted tubule (PCT), the Loop of Henle (LOH), and the distal convoluted tubule (DCT).
Proximal Convoluted Tubule (PCT):
The PCT is the initial segment of the renal tubule, extending from the Bowman's capsule that encloses the glomerulus. Its convoluted structure and microvilli-lined cells increase the surface area for reabsorption. The PCT reabsorbs glucose, amino acids, sodium, and water from the filtrate, ensuring essential...
2.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Prognostic Value of Spatial and Topological Features of Tumor Microenvironment in Classic Hodgkin Lymphoma.

Oncology research·2026
Same author

European cancer data sharing: Analyses of an international survey.

International journal of medical informatics·2026
Same author

Computational pathology model to predict recurrence-free survival in NMPUC patients on BCG-therapy.

NPJ precision oncology·2026
Same author

Multi-modal AI for comprehensive breast cancer prognostication.

Nature communications·2026
Same author

Prevalence of germline variants in USP8, USP48, CABLES1 and PAM in patients with pituitary adenomas.

European journal of endocrinology·2026
Same author

Spatially-resolved CD8<sup>+</sup> and CD34<sup>+</sup> computational immunohistochemistry indicators improve post-nephrectomy risk stratification in clear cell renal cell carcinoma.

Human pathology·2026

Related Experiment Video

Updated: Dec 26, 2025

An Efficient Sieving Method to Isolate Intact Glomeruli from Adult Rat Kidney
10:14

An Efficient Sieving Method to Isolate Intact Glomeruli from Adult Rat Kidney

Published on: November 1, 2018

14.4K

Data for glomeruli characterization in histopathological images.

Gloria Bueno1, Lucia Gonzalez-Lopez2, Marcial Garcia-Rojo3

  • 1VISILAB, Universidad de Castilla-La Mancha, Ciudad Real, Spain.

Data in Brief
|March 11, 2020
PubMed
Summary

This study provides whole slide imaging (WSI) datasets for glomerulosclerosis research. The data supports artificial intelligence (AI) algorithm development for quantitative nephropathology analysis.

Keywords:
Digital pathologyGlobal sclerotic glomerulusGlomeruli identificationNormal glomerulusWhole slide image

More Related Videos

Optical Clearing and Imaging of Immunolabeled Kidney Tissue
06:18

Optical Clearing and Imaging of Immunolabeled Kidney Tissue

Published on: July 22, 2019

10.9K
Whole-Kidney Three-Dimensional Staining with CUBIC
04:31

Whole-Kidney Three-Dimensional Staining with CUBIC

Published on: July 18, 2022

4.6K

Related Experiment Videos

Last Updated: Dec 26, 2025

An Efficient Sieving Method to Isolate Intact Glomeruli from Adult Rat Kidney
10:14

An Efficient Sieving Method to Isolate Intact Glomeruli from Adult Rat Kidney

Published on: November 1, 2018

14.4K
Optical Clearing and Imaging of Immunolabeled Kidney Tissue
06:18

Optical Clearing and Imaging of Immunolabeled Kidney Tissue

Published on: July 22, 2019

10.9K
Whole-Kidney Three-Dimensional Staining with CUBIC
04:31

Whole-Kidney Three-Dimensional Staining with CUBIC

Published on: July 18, 2022

4.6K

Area of Science:

  • Nephropathology
  • Medical Imaging
  • Artificial Intelligence

Background:

  • Glomerulosclerosis is a key indicator of kidney disease.
  • Accurate identification of glomeruli in whole slide images (WSI) is crucial for diagnosis.
  • Existing methods for glomeruli analysis can be computationally intensive.

Purpose of the Study:

  • To provide raw and processed whole slide imaging (WSI) datasets for glomerulosclerosis research.
  • To facilitate the development and comparison of artificial intelligence (AI) algorithms for quantitative nephropathology.
  • To support research on semantic segmentation for glomeruli classification.

Main Methods:

  • Generation of whole slide imaging (WSI) datasets within the European AIDPATH project.
  • Utilizing deep learning methods for glomeruli segmentation and classification.
  • Providing detected glomeruli as individual image files.

Main Results:

  • The dataset includes raw WSI data and segmented glomeruli.
  • The data is linked to a publication in Computer Methods and Programs in Biomedicine.
  • The dataset is suitable for training and validating AI models.

Conclusions:

  • The released dataset will accelerate AI-driven research in nephropathology.
  • This resource enables the creation and benchmarking of novel algorithms for glomeruli analysis.
  • The data promotes advancements in quantitative nephropathology using AI.