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Updated: Dec 26, 2025

Murine Model of Hindlimb Ischemia
Published on: January 21, 2009
An unusual case of upper limb ischemia in a marathon runner
William Gondoputro1, Saissan Rajendran1, David Celermajer2,3,4
1Department of Vascular Surgery, Royal Prince Alfred Hospital, Sydney, New South Wales, Australia.
Abstract:
Acute limb ischemia in young adults warrants thorough investigation to determine the underlying cause. Here, we present a case of acute upper limb ischemia in a marathon runner secondary to paradoxical embolism. The patient had associated deep venous thrombosis of the lower limb with multiple pulmonary emboli and patent foramen ovale. This case report emphasizes the under-recognition of intense endurance exercise as a risk factor for venous thromboembolism and highlights the potentially debilitating embolic sequelae of venous thromboembolism in patients with patent foramen ovale.
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