Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Space-time acoustofluidic tweezers for dynamic and selective manipulation of microparticles.

Science advances·2026
Same author

SonoPIN enables precise, noninvasive, and efficient intracellular delivery of PROTACs.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same author

The 2026 guided acoustic waves roadmap.

Journal of physics D: Applied physics·2026
Same author

FATE-MAP predicts teratogenicity and human gastrulation failure modes by integrating deep learning and mechanistic modeling.

Nature communications·2026
Same author

Optogenetic Rescue Reveals Spatiotemporal Rules of Germ-Layer Patterning.

bioRxiv : the preprint server for biology·2025
Same author

The Application and Comparison of the Pediatric Voice Handicap Index and Acoustic Analysis in Pediatric Benign Voice Disorders.

Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale·2025
Same journal

Microfluidic rare cell analysis beyond counting: workflow design from enrichment to multi-omics.

Lab on a chip·2026
Same journal

A sperm racetrack to separate sperm by swim speed.

Lab on a chip·2026
Same journal

Controlled encapsulation and droplet size prediction in two-step microfluidic double emulsions.

Lab on a chip·2026
Same journal

A particulate blood-mimicking fluid with physiological biconcave geometry for microscale hemorheology.

Lab on a chip·2026
Same journal

Multicellular sensor arrays fabricated by capillary stamping for pattern-based odor discrimination.

Lab on a chip·2026
Same journal

A real-time microfluidic surveillance system for multiplex detection of heavy metal contamination in wastewater.

Lab on a chip·2026
See all related articles

Related Experiment Video

Updated: Dec 26, 2025

Microparticle Manipulation by Standing Surface Acoustic Waves with Dual-frequency Excitations
06:51

Microparticle Manipulation by Standing Surface Acoustic Waves with Dual-frequency Excitations

Published on: August 21, 2018

7.4K

Low-frequency flexural wave based microparticle manipulation.

Hunter Bachman1, Yuyang Gu, Joseph Rufo

  • 1Department of Mechanical Engineering and Materials Science, Duke University, Durham, NC 27708, USA. tony.huang@duke.edu.

Lab on a Chip
|March 11, 2020
PubMed
Summary
This summary is machine-generated.

This study presents a low-cost acoustofluidic platform using flexural waves for precise microparticle and bio-sample manipulation. The device enables dynamic particle concentration and translation in open fluid wells for various biomedical applications.

More Related Videos

Fabrication and Operation of Acoustofluidic Devices Supporting Bulk Acoustic Standing Waves for Sheathless Focusing of Particles
10:14

Fabrication and Operation of Acoustofluidic Devices Supporting Bulk Acoustic Standing Waves for Sheathless Focusing of Particles

Published on: March 6, 2016

13.3K
A Microfluidic Platform for Precision Small-volume Sample Processing and Its Use to Size Separate Biological Particles with an Acoustic Microdevice
11:32

A Microfluidic Platform for Precision Small-volume Sample Processing and Its Use to Size Separate Biological Particles with an Acoustic Microdevice

Published on: November 23, 2015

14.2K

Related Experiment Videos

Last Updated: Dec 26, 2025

Microparticle Manipulation by Standing Surface Acoustic Waves with Dual-frequency Excitations
06:51

Microparticle Manipulation by Standing Surface Acoustic Waves with Dual-frequency Excitations

Published on: August 21, 2018

7.4K
Fabrication and Operation of Acoustofluidic Devices Supporting Bulk Acoustic Standing Waves for Sheathless Focusing of Particles
10:14

Fabrication and Operation of Acoustofluidic Devices Supporting Bulk Acoustic Standing Waves for Sheathless Focusing of Particles

Published on: March 6, 2016

13.3K
A Microfluidic Platform for Precision Small-volume Sample Processing and Its Use to Size Separate Biological Particles with an Acoustic Microdevice
11:32

A Microfluidic Platform for Precision Small-volume Sample Processing and Its Use to Size Separate Biological Particles with an Acoustic Microdevice

Published on: November 23, 2015

14.2K

Area of Science:

  • Biotechnology
  • Microfluidics
  • Acoustics

Background:

  • Microparticle and bio-sample manipulation is crucial in research and clinical settings.
  • Acoustic-based methods offer biocompatible and precise manipulation of small objects.
  • Existing methods often require complex designs.

Purpose of the Study:

  • To introduce a novel flexural wave-based acoustofluidic platform for microparticle manipulation.
  • To demonstrate dynamic particle concentration and translation in an open fluid well.
  • To explore the potential of this platform in biological and biomedical applications.

Main Methods:

  • Utilized low-frequency (4-6 kHz) commercial buzzers to generate flexural wave vibrations.
  • Investigated wave patterns numerically and experimentally.
  • Employed a phase difference between transducers for precise control of fluid vortices and particle clusters.

Main Results:

  • Achieved dynamic particle concentration in pressure nodes and trapping/manipulation in streaming vortices.
  • Demonstrated precision movement of fluid vortices and entrapped particle clusters.
  • Verified the effectiveness of flexural mode vibrations for acoustofluidic manipulation.

Conclusions:

  • The developed platform offers a simple, low-cost solution for acoustofluidic manipulation.
  • Its open fluidic chamber design is suitable for diverse biological, biochemical, and biomedical applications.
  • Potential applications include tumor spheroid generation, culture, and embryo manipulation.