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Updated: Dec 26, 2025

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Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery
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Case report: cranial angiosarcoma with multiple hemorrhagic brain metastasis in a child
Vanessa Lee1, Dominic Gessler1,2,3, Oguz Cataltepe4
1University of Massachusetts Medical School, Worcester, MA, USA.
Summary
Pediatric skull angiosarcoma is exceptionally rare. Aggressive multimodal treatment, including surgery and neoadjuvant therapy, may improve survival in children with this aggressive cancer.
Area of Science:
- Oncology
- Pediatric Oncology
- Surgical Oncology
Background:
- Angiosarcoma is a rare, aggressive cancer typically affecting adults.
- Pediatric angiosarcoma, especially of the skull with brain metastasis, is exceptionally rare.
- Limited data exists on clinical progression and established treatment guidelines for pediatric skull angiosarcoma.

