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Detection of Mesenteric Tumor Using Dynamic Contrast Enhanced MRI
Russell N Low1, Robert M Barone2, Bridgette Duggan3
1Department of Radiology, Sharp Memorial Hospital, San Diego, CA, USA. rlow52@yahoo.com.
Annals of Surgical Oncology
|March 12, 2020
Summary
Dynamic contrast-enhanced (DCE) MRI significantly improves the detection of mesenteric peritoneal metastases compared to conventional MRI. This novel technique enhances diagnostic accuracy for identifying tumor spread in the mesentery.
Area of Science:
- Radiology
- Oncology
- Medical Imaging
Background:
- Mesenteric peritoneal metastases pose diagnostic challenges.
- Conventional MRI has limitations in detecting small-volume tumors.
Purpose of the Study:
- To evaluate dynamic contrast-enhanced (DCE) MRI for detecting mesenteric peritoneal metastases.
- To compare the efficacy of DCE MRI against conventional MRI in identifying tumor spread.
Main Methods:
- Thirty-four patients underwent preoperative conventional MRI and DCE MRI.
- DCE MRI involved rapid imaging sequences over 6 minutes.
- Parametric maps of tumor vascularity were generated from DCE images.
- Oncologic surgeons and a radiologist reviewed images, comparing conventional MRI with DCE MRI plus parametric maps.
Main Results:
- DCE MRI demonstrated superior sensitivity (100%) and accuracy (97%) for upper and lower mesenteric tumors compared to conventional MRI.
- The addition of DCE MRI improved the accuracy of the Peritoneal Cancer Index (PCI) by over 10% in 46% of patients.
- DCE MRI significantly improved the accuracy of regional PCI calculations in specific areas.
Conclusions:
- DCE MRI is a valuable novel contrast tool for enhancing the detection of mesenteric tumors.
- This technique offers improved visualization of small-volume mesenteric tumors over conventional MRI.
