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Related Concept Videos

Mitral Stenosis III: Medical Management01:26

Mitral Stenosis III: Medical Management

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Mitral stenosis, a condition marked by the narrowing of the mitral valve, necessitates an integrated approach for effective management. This approach includes preventative measures, medical therapy, and surgical interventions to reduce symptoms and prevent complications.PreventionPrevention of mitral stenosis primarily focuses on reducing the incidence of bacterial infections, particularly streptococcal infections, which can lead to rheumatic fever and subsequent valvular damage. Timely...
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Related Experiment Video

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Percutaneous Pulmonary Valve Implantation.

Luca Giugno1, Alessia Faccini1, Mario Carminati2

  • 1Department of Pediatric and Adult Congenital Cardiology and Cardiac Surgery, IRCCS Policlinico San Donato, San Donato Milanese, Italy.

Korean Circulation Journal
|March 12, 2020
PubMed
Summary

Percutaneous pulmonary valve implantation (PPVI) offers a low-risk alternative to surgery for right ventricular outflow tract (RVOT) issues. This minimally invasive procedure is expanding to treat wider native RVOT, showing promising long-term results.

Keywords:
Congenital heart diseasePercutaneous pulmonary valve implantationTranscatheter procedure

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Area of Science:

  • Cardiology
  • Interventional Cardiology
  • Medical Devices

Background:

  • Percutaneous pulmonary valve implantation (PPVI) is an established, low-risk alternative to surgical repair for dysfunctional right ventricular outflow tracts (RVOT), particularly in patients with prior surgeries.
  • Technological advancements have expanded PPVI from treating only stenotic conduits to addressing wider native RVOT.
  • Key devices include the Melody transcatheter pulmonary valve (TPV) and Edwards Sapien valve, with newer options like Venus p-valve, Medtronic Harmony TPV, Alterra Adaptive Prestent, and Pulsta valve emerging.

Purpose of the Study:

  • To review the current landscape of percutaneous pulmonary valve implantation (PPVI) for right ventricular outflow tract (RVOT) dysfunction.
  • To highlight the evolving indications and available prosthetic devices for PPVI.
  • To emphasize the importance of preoperative evaluation for patient selection in PPVI.

Main Methods:

  • Review of current literature on percutaneous pulmonary valve implantation (PPVI) and available devices.
  • Analysis of indications, patient selection criteria, and procedural outcomes.
  • Synthesis of data on periprocedural mortality and reintervention rates.

Main Results:

  • PPVI demonstrates a low periprocedural mortality rate of approximately 1.4%.
  • Freedom from RVOT reintervention is high, ranging from 100% at 4 months to 70% at 70 months post-procedure.
  • The range of available prostheses allows for treatment of both stenotic conduits and wider native RVOT.

Conclusions:

  • Percutaneous pulmonary valve implantation (PPVI) is a safe and effective treatment for right ventricular outflow tract (RVOT) dysfunction.
  • Accurate preoperative assessment is crucial for successful patient selection and optimal outcomes.
  • Ongoing technological development continues to expand the applicability of PPVI.