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Updated: Dec 26, 2025
Flow Cytometry to Estimate Leukemia Stem Cells in Primary Acute Myeloid Leukemia and in Patient-derived-xenografts, at Diagnosis and Follow Up
Published on: March 26, 2018
[Modern Leukemia Diagnosis]
Pontus Lundberg1, Friedel Wenzel2, Julia Engels3,1
1Diagnostische Hämatologie, Universitätsspital Basel.
Abstract:
Modern Leukemia Diagnosis Abstract. Modern leukemia diagnosis is integrative as it includes the combination of results of different laboratory techniques: morphological cytology and histology as well as flow cytometric immunophenotyping and genomic analysis - covering different techniques from the morphological assessment of chromosomes to the analysis of point mutations in the genome. Many of these techniques are quantitative and allow not only for a precise diagnosis including prognostic information but also the option of measuring residual disease during treatment. The different techniques used are presented here.
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