Long-Term Trends in Postoperative Opioid Prescribing, 1994 to 2014

Catherine L Chen1, Molly Moore Jeffery1, Erin E Krebs1

  • 1Philip R. Lee Institute for Health Policy Studies at the University of California, San Francisco (Dr. Chen, Dr. Finlayson, Dr. Rodriguez-Monguio, Dr. Ward, and Dr. Dudley), San Francisco, CA; the Center for Healthcare Value, University of California, San Francisco (Dr. Chen), San Francisco, CA; the Department of Anesthesia and Perioperative Care, University of California, San Francisco (Dr. Chen and Dr. Schumacher), San Francisco, CA; OptumLabs Visiting Fellow (Dr. Chen), San Francisco, CA; the Department of Health Sciences Research, Mayo Clinic (Dr. Jeffery), Rochester, MN; the Department of Medicine, University of Minnesota Medical School (Dr. Krebs), Minneapolis, MN; the Center for Care Delivery and Outcomes Research, Minneapolis VA Health Care System (Dr. Krebs), Minneapolis, MN; the Department of Surgery, Memorial Sloan Kettering Cancer Center (Dr. Thiels), New York, NY; the Department of Orthopaedic Surgery, Mayo Clinic (Dr. Schwartz) Phoenix, AZ; the Center for Clinical Informatics and Improvement Research, University of California, San Francisco (Thombley), San Francisco, CA; the Department of Surgery, University of California, San Francisco (Dr. Finlayson), San Francisco, CA; the Department of Clinical Pharmacy, University of California, San Francisco (Dr. Rodriguez-Monguio), San Francisco, CA; the Medication Outcomes Center, University of California, San Francisco (Dr. Rodriguez-Monguio), San Francisco, CA; the Department of Orthopaedic Surgery, University of California, San Francisco (Dr. Ward), San Francisco, CA; and the Department of Medicine, University of California, San Francisco (Dr. Dudley), San Francisco, CA.

Summary

Postoperative opioid prescribing increased significantly after the introduction of long-acting opioids, particularly for orthopedic surgeries. High-dose prescriptions (≥350 MME) became more common, driven by long-acting formulations.

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