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Related Concept Videos

Cardiac Output II: Effect of Stroke Volume on Cardiac Output01:22

Cardiac Output II: Effect of Stroke Volume on Cardiac Output

Cardiac output (CO), the amount of blood the heart pumps per minute, is a parameter in cardiovascular physiology determined by stroke volume and heart rate. Stroke volume, the amount of blood pushed from one of the ventricles per heartbeat, is influenced by preload, afterload, and contractility.
Preload
Preload refers to the initial elongation of the cardiac myocytes before contraction and is related to the volume of blood filling the heart at the end of diastole, or end-diastolic volume. The...

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Related Experiment Video

Updated: Jun 8, 2026

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Stroke-mimics in stroke-units. Evaluation after changes imposed by randomized trials.

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  • 1Service de neuroradiologie diagnostique et interventionnelle, Centre Hospitalier Régional et Universitaire de Tours, France.

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Summary
This summary is machine-generated.

Improving stroke treatment requires better emergency service organization to reduce imaging delays. Identifying predictors for ischemic stroke versus stroke mimics aids in selecting patients for timely neuroimaging and reperfusion therapies.

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Area of Science:

  • Neurology
  • Emergency Medicine
  • Radiology

Background:

  • Expanding therapeutic windows for stroke necessitates optimizing emergency service organization.
  • Reducing unnecessary imaging exams is crucial to minimize treatment delays.

Purpose of the Study:

  • To analyze the link between rapid clinical evaluation and increased stroke over-suspicion, leading to excessive imaging.
  • To identify key predictors differentiating acute ischemic stroke from stroke mimics (SM).
  • To enhance patient selection for advanced neuroimaging and reperfusion therapies.

Main Methods:

  • Retrospective, observational, single-center cohort study.
  • Reviewed 736 patient files presenting with acute neurological symptoms.
  • Included patients undergoing CT scan or MRI between July 2016 and July 2017.

Main Results:

  • 52.3% of patients had acute ischemic infarct; 12.6% had stroke mimics; 35.1% had normal imaging.
  • Acute stroke was more common in elderly patients with specific risk factors (e.g., atrial fibrillation, hypertension) and symptoms (e.g., dysarthria, motor impairment).
  • Stroke mimics were associated with female patients, lower vascular risk factors, lower NIHSS scores, and specific neurological signs (e.g., decreased consciousness, posterior circulation symptoms).

Conclusions:

  • Nearly half of patients evaluated for stroke did not have acute lesions, highlighting the need for improved diagnostic accuracy.
  • Clinical assessment can provide indicators for acute stroke versus stroke mimics, though symptoms overlap.
  • A diagnostic algorithm is needed to guide urgent MRI for suspected stroke, especially with expanding treatment windows.