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Interaction Between Self-Expanding Transcatheter Heart Valves and Coronary Ostia: An Angiographically Based Analysis
Thomas Couture, Laurent Faroux, Lucia Junquera
1Quebec Heart & Lung Institute, Laval University, 2725 Chemin Ste-Foy, G1V4G5, Quebec City, Quebec, Canada. josep.rodes@criucpq.ulaval.ca.
Insights
The Evolut R/Pro valve is usually placed below the left coronary artery ostium. Shallower implantation (≤6mm) increases the risk of the valve being at or above the coronary ostia, potentially impacting future coronary access.
Area of Science:
- Cardiology
- Interventional Cardiology
- Medical Devices
Background:
- Transcatheter aortic valve replacement (TAVR) is a common procedure for aortic stenosis.
- Accurate positioning of the replacement valve is crucial to avoid complications.
- The CoreValve Evolut R/Pro (Medtronic) is a widely used TAVR prosthesis.
Purpose of the Study:
- To assess the positioning of the Evolut R/Pro valve relative to the left coronary artery (LCA) ostium.
- To evaluate how implantation depth affects the valve's relationship with the LCA ostium.
Main Methods:
- One hundred patients receiving an Evolut R/Pro valve underwent post-implantation angiography.
- Measurements included valve implantation depth and position relative to the LCA ostium.
- Coronary access issues post-TAVR were recorded.
Main Results:
- The Evolut R/Pro neo-valve was infraostial in 85% of cases.
- Implantation depth ≤6 mm was linked to a higher rate of supraostial or at-ostial positioning (25% vs 4%, P=.01).
- Coronary artery access was needed in 10% of patients at follow-up.
Conclusions:
- The Evolut R/Pro valve is predominantly positioned below the LCA ostium.
- Shallower implantation depths (≤6 mm) increase the likelihood of the neo-valve being at or above the coronary ostia.
- Further research is needed to understand the impact of high valve positioning on post-TAVR coronary access.
Objectives:
We sought to assess the position of the CoreValve Evolut R/Pro (Medtronic) with respect to the left coronary artery (LCA) ostium and evaluate the impact of implantation depth on this relationship.
Methods:
One hundred consecutive patients who received an Evolut R/Pro valve and had an adequate angiography following valve implantation were included. Angiographic measurements included valve implantation depth, the position of the Evolut R/Pro with respect to the LCA, and the distance between the neo-valve cusp and the LCA ostium. Coronary access issues following TAVR were also recorded.
Results:
Regarding the LCA ostium, the neo-valve of the Evolut R/Pro was supraostial, at the ostial level, and infraostial in 3%, 12%, and 85% of cases, respectively. When beneath the LCA ostium, the mean distance between the neo-valve and the floor of the LCA ostium was 4.1 ± 5.2 mm. An implantation depth ≤6 mm was associated with a higher rate of neo-valve at the ostial level or above (25% vs 4% for implantation depth >6 mm; P=.01). Accessing the coronary arteries was required in 10% of the patients at 12 ± 8 months post TAVR, and selective coronary angiography of the left and right coronary arteries was achieved in 60% and 40% of the cases, respectively.
Conclusions:
The Evolut R/Pro neo-valve was positioned below the LCA ostium in the vast majority of cases (85%), but an implantation depth ≤6mm was associated with a higher rate of neo-valve positioning at or above the coronary ostia level. Considering the current tendency of very high (aortic) valve implants to avoid conduction disturbances, future studies should determine the impact of high Evolut R/Pro positioning on coronary access issues post TAVR.
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