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Kidney Health for Everyone Everywhere - From Prevention to Detection and Equitable Access to Care
Philip Kam-Tao Li1, Guillermo Garcia-Garcia2, Siu-Fai Lui3
1Department of Medicine and Therapeutics, Carol and Richard Yu PD Research Centre, Prince of Wales Hospital, Chinese University of Hong Kong, Hong Kong, China.
Insights
Chronic kidney disease (CKD) is a growing global health crisis. Preventive measures, including risk factor modification and early intervention, are crucial to reduce its burden and healthcare costs.
Area of Science:
- Nephrology
- Public Health
- Preventive Medicine
Background:
- Chronic kidney disease (CKD) presents a significant and escalating global health challenge, projected to be the fifth leading cause of life lost by 2040.
- CKD imposes a substantial economic burden, with dialysis and transplantation consuming a considerable portion of healthcare budgets in high-income nations.
Discussion:
- Preventive strategies for CKD encompass primary prevention (risk factor modification, addressing structural abnormalities, and reducing exposure to environmental hazards and nephrotoxins).
- Secondary prevention in individuals with existing kidney disease focuses on blood pressure and glycemic control.
- Tertiary prevention for advanced CKD involves managing comorbidities like uremia and cardiovascular disease to delay or avoid renal replacement therapy.
Key Insights:
- CKD onset and progression are largely preventable through targeted interventions.
- A multi-faceted approach to prevention, including primary, secondary, and tertiary measures, is essential.
- Political will and specific national policies are vital to promote CKD awareness, screening, and management.
Outlook:
- There is an urgent need to enhance public, professional, and policymaker awareness regarding the importance of CKD prevention.
- Integrating specific CKD prevention policies into broader non-communicable disease strategies is recommended.
- Advancing preventive approaches can mitigate the escalating global burden and economic impact of chronic kidney disease.
Abstract:
The global burden of chronic kidney disease (CKD) is rapidly increasing with a projection of becoming the 5th most common cause of years of life lost globally by 2040. Aggravatingly, CKD is a major cause of catastrophic health expenditure. The costs of dialysis and transplantation consume up to 3% of the annual healthcare budget in high-income countries. Crucially, however, the onset and progression of CKD is often preventable. In 2020, the World Kidney Day campaign highlights the importance of preventive interventions - be it primary, secondary or tertiary. This complementing article focuses on outlining and analyzing measures that can be implemented in every country to promote and advance CKD prevention. Primary prevention of kidney disease should focus on the modification of risk factors and addressing structural abnormalities of the kidney and urinary tracts, as well as exposure to environmental risk factors and nephrotoxins. In persons with pre-existing kidney disease, secondary prevention, including blood pressure optimization and glycemic control, should be the main goal of education and clinical interventions. In patients with advanced CKD, management of co-morbidities such as uremia and cardiovascular disease is a highly recommended preventative intervention to avoid or delay dialysis or kidney transplantation. Political efforts are needed to proliferate the preventive approach. While national policies and strategies for non-communicable diseases might be present in a country, specific policies directed toward education and awareness about CKD screening, management and treatment are often lacking. Hence, there is an urgent need to increase the awareness of the importance of preventive measures throughout populations, professionals and policy makers.
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