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Mutations in disordered proteins as early indicators of nucleic acid changes triggering speciation

Sergio Forcelloni1, Andrea Giansanti2,3

  • 1Sapienza University of Rome, Department of Physics, P.le A. Moro 5, 00185, Roma, Italy. sergio.forcelloni@gmail.com.

Scientific Reports
|March 13, 2020
PubMed
Summary

Intrinsically disordered proteins (IDPs) drive early speciation, while ordered proteins (ORDPs) accelerate phenotypic divergence after speciation begins. This study reveals distinct roles for protein structural variants in evolution.

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