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Author Spotlight: Assessing the Cardiovascular Profile of Patients with Metabolic Syndrome
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Author Spotlight: Assessing the Cardiovascular Profile of Patients with Metabolic Syndrome

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Prevalence and impact of cardiovascular metabolic diseases on COVID-19 in China

Bo Li1, Jing Yang2,3, Faming Zhao4

  • 1Department of Cardiology, Zibo Central Hospital, Shandong University, No. 10, Sonth Shanghai Road, Zibo, 255000, People's Republic of China. libosubmit@163.com.

Clinical Research in Cardiology : Official Journal of the German Cardiac Society
|March 13, 2020
PubMed

Insights

Cardiovascular metabolic diseases increase COVID-19 severity and worsen outcomes. Patients with these conditions face higher risks of severe illness and cardiac injury from the novel coronavirus (COVID-19).

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Metabolic Disorders

Background:

  • Cardiovascular metabolic comorbidities are linked to increased susceptibility and severity of COVID-19.
  • Understanding this association is crucial for managing patients with 2019 novel coronavirus (2019-nCoV) disease (COVID-19).

Purpose of the Study:

  • To determine the association between cardiovascular metabolic diseases and the development of severe COVID-19.
  • To analyze the prevalence and incidence of these comorbidities in COVID-19 patients.

Main Methods:

  • A meta-analysis was conducted on six eligible studies involving 1527 patients.
  • Prevalence of cardiovascular metabolic diseases in COVID-19 patients was summarized.
  • Incidences of comorbidities in intensive care unit (ICU)/severe versus non-ICU/severe COVID-19 patients were compared using data from Embase and PubMed.

Main Results:

  • Prevalence rates for hypertension, cardio-cerebrovascular disease, and diabetes were 17.1%, 16.4%, and 9.7%, respectively.
  • Incidences of hypertension, cardio-cerebrovascular diseases, and diabetes were 2-3 times higher in severe COVID-19 cases.
  • Acute cardiac injury occurred in at least 8.0% of COVID-19 patients, with a 13-fold higher incidence in severe cases.

Conclusions:

  • Pre-existing cardiovascular metabolic diseases are associated with a greater risk of severe COVID-19.
  • These comorbidities significantly impact COVID-19 prognosis and can exacerbate cardiac damage.
  • COVID-19 infection can, in turn, worsen cardiac injury in affected patients.
Abstract

Keywords:
2019-nCoVCOVID-19Cardiac injuryCardiovascular metabolic diseases

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