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Chevalierinol A and B, two new neolignan sesquiterpenoids from Magnolia chevalieri
Pham Thi Ninh1,2, Chu Thi Thu Ha2,3, Tran Huy Thai2,3
1Institute of Chemistry, Vietnam Academy of Science and Technology, Ha Noi, Vietnam.
Abstract:
Two new neolignan sesquiterpenoids, chevalierinol A (1) and chevalierinol B (2), were isolated from the ethyl acetate extract of Magnolia chevalieri leaves, together with twelve known compounds (3-14). Their structures were elucidated by analysis of spectroscopic data including 1D, 2D and mass spectra and compared with the reported data. Compounds 1, 3, 4, 6, 7, 10 were evaluated for their inhibitory effect against lipopolysaccharide (LPS)-induced nitric oxide (NO) production in RAW264.7 macrophage cells.
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