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Moving exercise research in multiple sclerosis forward (the MoXFo initiative): Developing consensus statements for
Ulrik Dalgas1, Lars G Hvid1, Gert Kwakkel2
1Section for Sport Science, Department of Public Health, Aarhus University, Aarhus, Denmark.
Multiple Sclerosis (Houndmills, Basingstoke, England)
|March 13, 2020
Summary
Exercise is crucial for managing multiple sclerosis (MS). An international expert partnership aims to overcome research barriers by establishing a framework for future exercise studies in MS, enhancing quality and outcomes for patients.
Area of Science:
- Neurology
- Rehabilitation Medicine
- Exercise Science
Background:
- Exercise is vital for managing multiple sclerosis (MS) due to its wide-ranging benefits.
- Despite increasing research, study quality and content barriers impede progress in exercise interventions for MS.
- An international collaboration of experts has formed to address these challenges and advance the research agenda.
Purpose of the Study:
- To establish a collaborative framework for improving the quality and scope of exercise research in multiple sclerosis.
- To identify and address key barriers hindering progress in understanding exercise's role in MS management.
- To develop recommendations for future research directions in exercise for individuals with MS.
Main Methods:
- An international expert panel convened to identify urgent research areas and establish a framework.
- Five key themes were identified: Definitions and terminology, Study methodology, Reporting and outcomes, Adherence to exercise, and Mechanisms of action.
- Five expert groups were formed to outline challenges and provide recommendations within each theme, with planned collaboration with MS organizations.
Main Results:
- Identification of five critical themes requiring attention to advance exercise research in MS.
- Formation of expert groups tasked with detailing challenges and proposing solutions for each theme.
- A collaborative framework is being developed to guide future research and improve study quality.
Conclusions:
- A structured, multi-expert approach is essential to overcome existing barriers in MS exercise research.
- Collaboration with people with MS and relevant organizations is integral to the framework's success.
- This initiative aims to enhance the quality and impact of exercise studies, ultimately benefiting individuals with MS.
