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Related Concept Videos

Lifecycle of Erythrocytes01:22

Lifecycle of Erythrocytes

Erythrocytes, also known as red blood cells, constantly move through blood capillaries. As a result, they damage their plasma membrane due to the continuous friction. Typically, after 100 to 120 days, erythrocytes become rigid and fragile as they wear out. As they pass through small vessels in the spleen and liver, they can get trapped and break apart into fragments.
The resident phagocytic macrophages deal with these damaged cells by engulfing them and separating their globin and heme groups.

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Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload
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Preventing skin staining: an effective iron infusion protocol.

Clare Margaret Crowley1, Gabriela McMahon2, Joanna Desmond2

  • 1Mid-Western Intern Network, University Hospital Limerick, Limerick, Ireland.

International Journal of Health Care Quality Assurance
|March 13, 2020
PubMed
Summary

Implementing a new intravenous iron infusion protocol effectively prevented skin staining in patients. This quality improvement initiative ensured safer administration and improved patient communication regarding potential side effects.

Keywords:
Clinical incidentIntravenous ironObstetricsQuality improvement

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Area of Science:

  • Medical Sciences
  • Nursing Practice
  • Patient Safety

Background:

  • Skin staining from intravenous iron infusions, though rare, can be permanent and distressing.
  • Intravenous iron is crucial for treating anemia in pregnancy.
  • Previous incidents highlighted the need for improved administration protocols.

Purpose of the Study:

  • To implement a safe and effective intravenous iron infusion protocol.
  • To prevent the occurrence of skin staining in patients receiving IV iron.
  • To enhance patient safety and satisfaction during iron therapy.

Main Methods:

  • A mixed-methods approach was employed, including staff education and auditing.
  • Surveys assessed healthcare professionals' adherence to the protocol.
  • Patient feedback and information leaflets were utilized to gauge understanding and experience.

Main Results:

  • No instances of skin staining or severe adverse reactions were observed over an eight-week period.
  • Staff compliance with the protocol reached 53%, with 46% informing patients of staining risks.
  • High adherence to flushing procedures (92% pre-infusion, 88% post-infusion) was reported.

Conclusions:

  • The implemented protocol was effective in preventing skin staining and adverse events.
  • While compliance and patient information rates require improvement, the project demonstrates success.
  • Ensuring patients are informed and utilizing evidence-based protocols is vital for managing intravenous iron therapy.