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Updated: Dec 26, 2025

Cross-Modal Multivariate Pattern Analysis
Published on: November 9, 2011
Medial temporal lobe regions mediate complex visual discriminations for both objects and scenes: A process-based view
Ashley V Lawrence1, Jose Cardoza1, Lee Ryan1,2
1Department of Psychology, University of Arizona, Tucson, Arizona, USA.
Abstract:
Debate continues regarding the role of medial temporal lobe regions in object and scene processing. Considerable evidence indicates that the perirhinal cortex (PRC) plays an important role in the perception of objects-namely, in disambiguating complex objects that share conjunctions of features. These findings support a content-specific view of medial temporal lobe functioning in which PRC is critically important for processing complex objects, while the parahippocampal cortex (PHC) and hippocampus (HC) may be selectively engaged during scene processing. However, emerging evidence from both animal and human studies suggest that the PRC is sensitive to spatial configural information as well as object information. In this fMRI study, we observed preliminary evidence for BOLD activation in the PRC during a complex visual discrimination task for objects and scenes, as well as robust activation for both stimulus types in PHC and HC. The results are discussed in light of a recent process-based model of medial temporal lobe functioning.
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