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Related Concept Videos

Chirality02:25

Chirality

28.8K
Chirality is a term that describes the lack of mirror symmetry in an object. In other words, chiral objects cannot be superposed on their mirror images. For example, our feet are chiral, as the mirror image of the left foot, the right foot, cannot be superposed on the left foot.
Chiral objects exhibit a sense of handedness when they interact with another chiral object. For example, our left foot can only fit in the left shoe and not in the right shoe. Achiral objects — objects that have...
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Chirality in Nature02:30

Chirality in Nature

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Chirality is the most intriguing yet essential facet of nature, governing life’s biochemical processes and precision. It can be observed from a snail shell pattern in a macroscopic world to an amino acid, the minutest building block of life. Most of the snails around the world have right-coiled shells because of the intrinsic chirality in their genes. All the amino acids present in the human body exist in an enantiomerically pure state, except for glycine - the sole achiral amino acid.
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Properties of Enantiomers and Optical Activity02:24

Properties of Enantiomers and Optical Activity

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It is essential to understand the difference between chiral and achiral interactions and the implications thereof in optical activity and their applications. Just as our feet, which are chiral, interact uniquely with chiral objects, such as a pair of shoes, but identically with achiral socks, enantiomers of a molecule exhibit different properties only when they interact with other chiral media. An example of a significant implication from this facet is the phenomenon known as optical activity,...
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Prochirality02:05

Prochirality

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The concept of prochirality leads to the nomenclature of the individual faces of a molecule and plays a crucial role in the enantioselective reaction. It is a concept where two or more achiral molecules react to produce chiral products. A typical process is the reaction of an achiral ketone to generate a chiral alcohol. Here, the achiral reactant reacts with an achiral reducing agent, sodium borohydride, to generate an equimolar mixture of the chiral enantiomers of the product. For example, an...
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Molecules with Multiple Chiral Centers02:25

Molecules with Multiple Chiral Centers

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Molecules that possess multiple chiral centers can afford a large number of stereoisomers. For instance, while some molecules like 2-butanol have one chiral center, defined as a tetrahedral carbon atom with four different substituents attached, several molecules like butane-2,3-diol have multiple chiral centers. A simple formula to predict the number of stereoisomers possible for a molecule with n chiral centers is 2n. However, there can be a lower number where some of the stereoisomers are...
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Related Experiment Video

Updated: Dec 26, 2025

An Electrochemical Cholesteric Liquid Crystalline Device for Quick and Low-Voltage Color Modulation
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Optical circular dichroism engineering in chiral metamaterials utilizing a deep learning network.

Zilong Tao, Jie You, Jun Zhang

    Optics Letters
    |March 13, 2020
    PubMed
    Summary

    A new deep learning (DL) model accurately predicts the chiroptical response of 2D chiral metamaterials. This AI approach is significantly faster than traditional methods, accelerating photonic device design.

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    Area of Science:

    • Optics and Photonics
    • Materials Science
    • Computational Physics

    Background:

    • Chiral metamaterials exhibit unique light-matter interactions.
    • Predicting chiroptical responses is crucial for designing advanced photonic devices.
    • Traditional methods like RCWA are computationally intensive.

    Purpose of the Study:

    • To develop and validate a deep learning (DL) algorithm for predicting the chiroptical response of 2D chiral metamaterials.
    • To compare the DL approach with the rigorous coupled wave analysis (RCWA) method.
    • To demonstrate the potential of DL in accelerating metamaterial design.

    Main Methods:

    • A deep neural network (DL) model was developed to predict chiroptical responses.
    • Rigorous coupled wave analysis (RCWA) was used for comparison.
    • The study focused on 2D chiral metamaterials with U-like, T-like, and I-like nanostructures.
    • Circular dichroism (CD) in higher-order diffracted beams was analyzed.

    Main Results:

    • The DL model accurately predicted the chiroptical response (CD) of 2D chiral metamaterials.
    • A common feature observed was the strongest CD response in third-order diffracted beams.
    • The DL approach achieved a computational speed four orders of magnitude faster than RCWA.

    Conclusions:

    • Deep learning offers a highly accurate and significantly faster alternative to RCWA for predicting chiroptical responses.
    • The developed DL model shows great potential for exploring chiroptical interactions in metamaterials.
    • This work accelerates the design of hypersensitive photonic devices utilizing chiral metamaterials.