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Fetuin-a expression profile in mouse and human adipose tissue
Abdelkrim Khadir1, Sina Kavalakatt2, Dhanya Madhu2
1Genetics and Bioinformatics department, Research Division, Dasman Diabetes Institute, Kuwait City, Kuwait.
Fetuin-A (Fet-A) is expressed in mouse adipose tissue but minimally in human adipose tissue, suggesting limited systemic contribution from human fat. Local action in visceral fat may still occur.
Area of Science:
- Metabolic disease research
- Adipokine and hepatokine signaling
- Cellular biology of adipose tissue
Background:
- Fetuin-A (Fet-A) is a known hepatokine implicated in metabolic diseases.
- Its role as an adipokine and its expression in adipose tissue remain unclear.
- Previous studies suggest a potential link between Fet-A and metabolic dysfunction.
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