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Human Neural Organoids for Studying Brain Cancer and Neurodegenerative Diseases

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Published on: June 28, 2019

[Basal ganglia calcification].

E Auffray-Calvier¹, A Lintia-Gaultier¹, R Bourcier¹

¹Service de neuroradiologie, hôpital René-et-Guillaume-Laënnec, boulevard Jacques-Monod, 44093 Saint-Herblain cedex 1, France.

La Revue De Medecine Interne

|March 14, 2020

Summary

This summary is machine-generated.

Basal ganglia calcifications, common with aging, can indicate underlying diseases. Analyzing calcification patterns with MRI aids diagnosis of neurological symptoms.

Keywords:

Brain Calcifications IRM Magnetic resonance imaging Système nerveux central

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Area of Science:

Neurology
Radiology
Neuroimaging

Background:

Basal ganglia calcifications are common on CT scans, especially in the globus pallidus.
Frequency increases with age after 50, but pathological causes exist.
Calcifications can occur in gray nuclei, posterior fossa, or white matter.

Purpose of the Study:

To provide diagnostic aid for basal ganglia calcifications.
To correlate calcification topography with underlying pathologies.
To evaluate the utility of MRI sequences in diagnosing these conditions.

Main Methods:

Analysis of calcification topography on cerebral CT scans.
Study of various MRI sequences.
Correlation with clinical and biological data.

Main Results:

Unilateral calcifications often suggest acquired origins.
Bilateral calcifications may indicate acquired or genetic origins, prompting investigation of phosphocalcic metabolism.
Calcifications can be associated with neurological symptoms like Parkinsonism, psychiatric disorders, epilepsy, or headaches.

Conclusions:

Topographical analysis of basal ganglia calcifications is crucial for diagnosis.
MRI sequences offer valuable insights beyond CT findings.
Integrating imaging findings with clinical and biological data aids in identifying underlying causes and guiding patient management.