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Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
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Prevalence of atrial fibrillation in acute ischemic stroke patients: A hospital-based study from India

Deepak Goel1, Rekha Gupta2, Tulika Keshri3

  • 1Department of Neurology, Himalayan Hospital of Medical Sciences, Swami Ram Himalayan University, Dehradun, Uttarakhand, India.

Brain Circulation
|March 14, 2020
PubMed

Insights

Atrial fibrillation (AF) affects 25% of acute ischemic stroke patients, particularly the elderly and women. Early detection of AF is crucial for effective secondary stroke prevention and improved patient outcomes.

Area of Science:

  • Neurology
  • Cardiology
  • Public Health

Background:

  • Secondary stroke prevention is critical for reducing disability and mortality from recurrent cerebrovascular events.
  • Identifying specific risk factors is essential for effective secondary stroke prevention strategies.

Purpose of the Study:

  • To determine the prevalence of persistent or paroxysmal atrial fibrillation (AF) in patients who have experienced an acute ischemic stroke.
  • To investigate the association between AF and stroke characteristics and patient outcomes.

Main Methods:

  • A hospital-based prospective study included acute ischemic stroke patients from January 2016 to December 2018.
  • Risk factor analysis involved clinical history, physical examination, and assessments including NIHSS, LDL-C, HbA1c, Homocysteine, echocardiography, ECG, 24-hour Holter monitoring, and cerebral angiography.
  • Patient outcomes were evaluated at 90-day follow-up using the Modified Rankin Scale.

Main Results:

  • The study included 246 acute ischemic stroke patients (69.5% male, 30.5% female) with a mean age of 61.4 years.
  • Atrial fibrillation (AF) was detected in 62 patients (25.2%), identified through conventional ECG or 24-hour Holter monitoring.
  • A significant proportion of patients (12.4%) were under 45 years old.

Conclusions:

  • Atrial fibrillation is present in approximately 25% of acute ischemic stroke patients.
  • AF is more prevalent in elderly patients, females, and those with larger atrial size.
  • The presence of AF in stroke patients is associated with poorer neurological outcomes.
Abstract

Keywords:
Cardioembolic strokeischemic strokesecondary prevention

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